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D184

Diethylamine NONOate sodium salt hydrate

≥97% (NMR), crystalline, nitrix oxide donor

Synonym(s):

1,1-Diethyl-2-hydroxy-2-nitroso-hydrazine sodium, 2-(N,N-Diethylamino)-diazenolate 2-oxide sodium salt hydrate, DEA NONOate sodium salt hydrate, Diethylamine/nitric oxide complex sodium salt hydrate

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About This Item

Linear Formula:
(CH3CH2)2N–N(N=O)O- Na+ xH2O
CAS Number:
Molecular Weight:
155.13 (anhydrous basis)
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥97% (NMR)
Form:
crystalline
Quality level:
Storage condition:
desiccated, protect from light
Pricing and availability is not currently available.
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Product Name

Diethylamine NONOate sodium salt hydrate, ≥97% (NMR)

Quality Level

assay

≥97% (NMR)

form

crystalline

storage condition

desiccated, protect from light

color

white

mp

45 °C (lit.)

solubility

H2O: >10 mg/mL, methanol: >25 mg/mL

shipped in

dry ice

storage temp.

−20°C

SMILES string

O.[Na+].CCN(CC)N([O-])N=O

InChI

1S/C4H10N3O2.Na.H2O/c1-3-6(4-2)7(9)5-8;;/h3-4H2,1-2H3;;1H2/q-1;+1;

InChI key

BVCZSYKIXSAMOT-UHFFFAOYSA-N

Application

Diethylamine NONOate sodium salt hydrate has been used as a nitric oxide donor to evaluate endothelium-independent dilation. It has also been used to determine the level of nitric oxide in cell free systems.

Biochem/physiol Actions

Diethylamine NONOate is a complex of diethylamine with nitric oxide used to generate a controlled release of nitric oxide in solution.

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This Item
S7198N3139M3935
form

crystalline

form

solid

form

powder

form

powder

assay

≥97% (NMR)

assay

≥98% (HPLC)

assay

≥98% (HPLC), ≥98% (spectrophotometric assay)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

storage temp.

−20°C

storage temp.

room temp

storage temp.

−20°C

storage temp.

room temp

storage condition

desiccated, protect from light

storage condition

-

storage condition

-

storage condition

-

solubility

H2O: >10 mg/mL, methanol: >25 mg/mL

solubility

DMSO: 10 mg/mL, clear

solubility

H2O: 50 mg/mL

solubility

DMSO: 5 mg/mL, clear


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Wilkaniec A, et al.
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The functional and structural changes in the basilar artery due to overpressure blast injury
Toklu HZ, et al.
Journal of Cerebral Blood Flow and Metabolism, 35(12), 1950-1956 (2015)
Francesco Tamagnini et al.
The Journal of physiology, 591(16), 3963-3979 (2013-05-15)
Synaptic plasticity in perirhinal cortex is essential for recognition memory. Nitric oxide and endocannabinoids (eCBs), which are produced in the postsynaptic cell and act on the presynaptic terminal, are implicated in mechanisms of long-term potentiation (LTP) and long-term depression (LTD)



Global Trade Item Number

SKUGTIN
D184-50MG04061833261309
D184-25MG04061833560877

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