D0125

Dansyl-L-alanine cyclohexylammonium salt

≥98% (TLC), suitable for protein expression

• Synonym(s): N-[[5-(Dimethylamino)-1-naphthalenyl]sulfonyl]- L-alanine cyclohexylammonium salt
• Empirical Formula (Hill Notation): C₁₅H₁₈N₂O₄S · C₆H₁₃N
• CAS Number: 53332-27-7
• Molecular Weight: 421.55
• NACRES: NA.26
• PubChem Substance ID: 329798584
• UNSPSC Code: 12352209
• EC Number: 258-478-3
• MDL number: MFCD00038927

Properties

• Product Name: Dansyl-L-alanine cyclohexylammonium salt, fluorescent amino acid
• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• technique(s): protein expression: suitable
• storage temp.: −20°C
• SMILES string: NC1CCCCC1.C[C@H](NS(=O)(=O)c2cccc3c(cccc23)N(C)C)C(O)=O
• InChI: 1S/C15H18N2O4S.C6H13N/c1-10(15(18)19)16-22(20,21)14-9-5-6-11-12(14)7-4-8-13(11)17(2)3;7-6-4-2-1-3-5-6/h4-10,16H,1-3H3,(H,18,19);6H,1-5,7H2/t10-;/m0./s1
• InChI key: CZUBQNQWSOLSJH-PPHPATTJSA-N

Description

Application

Alanine conjugated to the fluorophore 5-(dimethylamino)naphthalene-1-sulfonyl (dansyl). The unnatural amino acid has been incorporated into expressed proteins by use of a mutated aminoacyl-tRNA synthetase specific for dansylalanine.[1]

Biochem/physiol Actions

Dansyl-L-alanine contains an N-terminal fluorophore (dansyl) making it useful as a fluorescent marker/probe. Dansylalanine can be incorporated into proteins by newly developing techniques that expand the genetic code.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable