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C8857

ProteoMass Cytochrome c MALDI-MS Standard

vial of 10 nmol, (M+H+) 12,361.96 Da by calculation

Synonym(s):

Cytochrome c from equine heart, Cytochrome c from horse heart

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.24
MDL number:
Pricing and availability is not currently available.
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product line

ProteoMass

Quality Segment

form

solid

mol wt

(M+H+) 12,361.96 Da by calculation

packaging

vial of 10 nmol

technique(s)

mass spectrometry (MS): suitable

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Application

Protein calibration standard for MALDI-MS instruments.
The specific sites and extent of oxidation in horse cytochrome c treated with H2O2 and UV were characterized. It was suggested that the state of these sites could be used as a biomarker for the oxidative environment in a cell.

Biochem/physiol Actions

Cytochrome c is primarily known as an electron-carrying mitochondrial protein. The transition of cytochrome c between the ferrous and ferric states within the cell makes it an efficient biological electron-transporter and it plays a vital role in cellular oxidations in both plants and animals. It is generally regarded as a universal catalyst of respiration, forming an essential electron-bridge between the respirable substrates and oxygen

Other Notes

Legal Information

ProteoMass is a trademark of Sigma-Aldrich Co. LLC

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This Item
C2436C3131C2037
technique(s)

mass spectrometry (MS): suitable

technique(s)

cell based assay: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell based assay: suitable

product line

ProteoMass

product line

-

product line

-

product line

-

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

application(s)

cell analysis

application(s)

-

application(s)

cell analysis

mol wt

(M+H+) 12,361.96 Da by calculation

mol wt

12,588 Da

mol wt

12327 Da

mol wt

12327 Da

packaging

vial of 10 nmol

packaging

-

packaging

-

packaging

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

300


Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Chris L Bergstrom et al.
Proceedings of the National Academy of Sciences of the United States of America, 110(16), 6269-6274 (2013-04-12)
The release of cytochrome c from mitochondria is a key signaling mechanism in apoptosis. Although extramitochondrial proteins are thought to initiate this release, the exact mechanisms remain unclear. Cytochrome c (cyt c) binds to and penetrates lipid structures containing the
Gabriel Ichim et al.
Molecular cell, 51(5), 632-646 (2013-09-17)
The neurotrophin receptor TrkC was recently identified as a dependence receptor, and, as such, it triggers apoptosis in the absence of its ligand, NT-3. The molecular mechanism for apoptotic engagement involves the double cleavage of the receptor's intracellular domain, leading
Margareta R A Blomberg et al.
Biochimica et biophysica acta, 1827(7), 826-833 (2013-04-27)
The membrane-bound enzyme cNOR (cytochrome c dependent nitric oxide reductase) catalyzes the reduction of NO in a non-electrogenic process. This is in contrast to the reduction of O2 in cytochrome c oxidase (CcO), the other member of the heme-copper oxidase



Global Trade Item Number

SKUGTIN
C8857-5X1VL04061838188076
C8857-1VL04061833296011

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