A5474

L-Aspartic acid

• Synonym(s): (S)-(+)-Aminosuccinic acid, (S)-Aminobutanedioic acid
• Linear Formula: HO₂CCH₂CH(NH₂)CO₂H
• CAS Number: 56-84-8
• Molecular Weight: 133.10
• EC Number: 200-291-6
• UNSPSC Code: 12352209
• NACRES: NA.26
• Beilstein/REAXYS Number: 1723530
• MDL number: MFCD00002616

Properties

• biological source: non-animal source
• Quality Level: 400
• assay: ≥98.5%
• form: crystalline powder
• technique(s): cell culture | mammalian: suitable
• impurities: endotoxin, heavy metals, trace metals, residual solvents, tested
• mp: >300 °C (dec.) (lit.)
• solubility: 1 M HCl: 50 mg/mL
• suitability: suitable for manufacturing use
• application(s): pharmaceutical (small molecule)
• foreign activity: cytotoxicity, tested
• SMILES string: N[C@@H](CC(O)=O)C(O)=O
• InChI: 1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
• InChI key: CKLJMWTZIZZHCS-REOHCLBHSA-N
• Gene Information: human ... CA1(759), CA2(760) ; rat ... Grin2a(24409)

Description

General description

Our SAFC^® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program.

M-Clarity Program

Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service.

To request documentation for this product, please contact Customer Support and select ‘Product Documentation′. Please note that access to the documentation for this product requires a confidentiality disclosure agreement.

Application

L-Aspartic acid is one of the 23 proteinogenic amino acids. It is a non-essential amino acid. It is used as a cell culture media component for the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies.

Biochem/physiol Actions

Principal neurotransmitter for fast synaptic excitation.

Legal Information

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves