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D7816

1,2-Di-O-lauryl-rac-glycero-3-glutaric acid 6′-methylresorufin ester

lipase substrate, solid

Synonym(s):

Chromogenic lipase substrate

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About This Item

MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32
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Product Name

1,2-Di-O-lauryl-rac-glycero-3-glutaric acid 6′-methylresorufin ester, lipase substrate

Quality Segment

form

solid

storage temp.

2-8°C

SMILES string

CCCCCCCCCCCCOCC(COC(=O)CCCC(=O)Oc1ccc2N=C3C=CC(=O)C=C3Oc2c1C)OCCCCCCCCCCCC

InChI

1S/C45H69NO8/c1-4-6-8-10-12-14-16-18-20-22-31-50-34-38(51-32-23-21-19-17-15-13-11-9-7-5-2)35-52-43(48)25-24-26-44(49)53-41-30-29-40-45(36(41)3)54-42-33-37(47)27-28-39(42)46-40/h27-30,33,38H,4-26,31-32,34-35H2,1-3H3

InChI key

JEGLJLCZRAWOBI-UHFFFAOYSA-N

Application

Chromogenic substrate for lipase

Biochem/physiol Actions

1,2-Di-O-lauryl-rac-glycero-3-glutaric acid 6′-methylresorufin ester (DGGR) is more pancreas-specific. Hence the DGGR lipase assay may be preferred as a substitute to spec cPL in diagnostic cases with suspected pancreatitis.


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Global Trade Item Number

SKUGTIN
D7816-10MG04061832923840

Questions

  1. Do you have informatoin on the molar extinction coefficient of 1,2-Di-O-lauryl-rac-glycero-3-glutaric acid 6′-methylresorufin ester? Thanks

    1 answer
    1. This product does not absorb strongly in the visible spectrum. The extinction coefficient has not been measured. Note that Resorufin sodium salt has a molar extinction coefficient of 73,000 in 0.1 M Tris-HCl buffer, pH 8.0, containing 0.1 M NaCl. This value is likely quite similar to that of the hydrolysis product of D7816, which would be 6-Methylresorufin sodium salt.

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