04473
2,4-Pyridinedicarboxylic acid
≥98.0%
Synonym(s):
Lutidinic acid
Sign In to View Organizational & Contract Pricing.
Select a Size
Change View
| Pack Size | SKU | Availability | Price |
|---|
About This Item
Empirical Formula (Hill Notation):
C7H5NO4
CAS Number:
Molecular Weight:
167.12
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352106
EC Number:
207-892-2
MDL number:
Beilstein/REAXYS Number:
131631
Pricing and availability is not currently available.
Quality Segment
assay
≥98.0%, 98.0-102.0% (T)
InChI
1S/C7H5NO4/c9-6(10)4-1-2-8-5(3-4)7(11)12/h1-3H,(H,9,10)(H,11,12)
InChI key
MJIVRKPEXXHNJT-UHFFFAOYSA-N
Application
2,4-Pyridinedicarboxylic acid is an in vitro and in cell inhibitor, as well as a known inhibitor of the histone lysine demethylases. 2,4-Pyridinedicarboxylic acid has been used in a study to determine that ruthenium(II) complexes exert antimetastatic effects on several tumor cell lines in vitro, achieved mostly by the effect on cell adhesion, migration and angiogenesis. . 2,4-Pyridinedicarboxylic acid has been used in a study to develop an assay that represents the first report of a RapidFire mass spectrometery assay for an epigenetics target.
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥98.0%, 98.0-102.0% (T) | assay - | assay ≥99.5% (T) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 200 | Quality Level 100 | Quality Level 200 |
Still not finding the right product?
Explore all of our products under 2,4-Pyridinedicarboxylic acid
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Line H Kristensen et al.
The FEBS journal, 279(11), 1905-1914 (2012-03-17)
Dynamic methylations and demethylations of histone lysine residues are important for gene regulation and are facilitated by histone methyltransferases and histone demethylases (HDMs). KDM5B/Jarid1B/PLU1 is an H3K4me3/me2-specific lysine demethylase belonging to the JmjC domain-containing family of histone demethylases (JHDMs). Several
Sue E Hutchinson et al.
Journal of biomolecular screening, 17(1), 39-48 (2011-08-24)
A high-throughput RapidFire mass spectrometry assay is described for the JMJD2 family of Fe(2+), O(2), and α-ketoglutarate-dependent histone lysine demethylases. The assay employs a short amino acid peptide substrate, corresponding to the first 15 amino acid residues of histone H3
Florina Vlad et al.
Physiologia plantarum, 140(2), 199-207 (2010-06-18)
Prolyl 4-hydroxylases (P4Hs) catalyze the proline hydroxylation, a major post-translational modification, of hydroxyproline-rich glycoproteins. Two carnation petal P4H cDNAs, (Dianthus caryophyllus prolyl 4-hydroxylase) DcP4H1 and DcP4H2, were identified and characterized at the gene expression and biochemical level in order to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 143618-100G | 04061838734921 |
| 143618-500G | 04061832278599 |
| 04473-5G | 04061838630681 |