SML1969

Linoleamide

≥98% (HPLC)

• Synonym(s): (9Z,12Z)-9,12-Octadecadienamide, Linoleic acid amide
• Empirical Formula (Hill Notation): C₁₈H₃₃NO
• CAS Number: 3999-01-7
• Molecular Weight: 279.46
• UNSPSC Code: 12352202
• NACRES: NA.77
• MDL number: MFCD00798239
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Properties

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: −20°C
• SMILES string: NC(CCCCCCC/C=C\C/C=C\CCCCC)=O
• InChI: 1S/C18H33NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10H,2-5,8,11-17H2,1H3,(H2,19,20)/b7-6-,10-9-
• InChI key: SFIHQZFZMWZOJV-HZJYTTRNSA-N

Description

Biochem/physiol Actions

Linoleamide is an endogenous primary fatty acid amide (PFAM) signaling lipid that modulates intracellular Ca2+ homeostasis. It has been shown to inhibit of SPCA2, a Golgi secretory pathway Ca(2+)-ATPase that transports ions of Ca2+ and Mn2+ and also to inhibit SPCA1a and the Ca2+-ATPase activity of three sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA) pump isoforms. It is thought to be involved in a variety of biological activities including regulation of sleep.

Modulator of intracellular Ca2+ homeostasis; Inhibitor of SPCA2, a Golgi secretory pathway Ca(2+)-ATPase that transports ions of Ca2+ and Mn2+

Linoleamide is an endogenous lipid, that stimulates sleep in cats, rats and humans.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable