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HTR2B

5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled

Synonimy:
5-HT(2B), 5-HT2B
Gatunek:
Human HTR2B (3357), Mouse Htr2b (15559), Rat Htr2b (29581), chicken HTR2B (395581), Zebrafish htr2b (751784), dog HTR2B (403881), cow HTR2B (407135), Horse HTR2B (100057052), domestic cat HTR2B (101095762), Domestic Rabbit HTR2B (100343392) ...Więcej
Identyfikator UniProtKB:
P41595, B2R9D5, Q53TI1, Q62221, Q6P523
Identyfikator genu:
  • Human(3357) Summary: This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. [provided by RefSeq, Oct 2011]
  • Mouse(15559) 5-hydroxytryptamine (serotonin) receptor 2B
  • Rat(29581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • chicken(395581) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Zebrafish(751784) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • dog(403881) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • cow(407135) 5-hydroxytryptamine (serotonin) receptor 2B
  • Horse(100057052) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic cat(101095762) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • Domestic Rabbit(100343392) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • sheep(101106827) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • naked mole-rat(101699201) 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • domestic guinea pig(100135546) 5-hydroxytryptamine (serotonin) receptor 2B

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
B175
BW 723C86, ≥98% (HPLC),
Gatunek
human
1430000
Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Y0000776
Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Y0000777
Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
M110
α-Methylserotonin maleate salt, ≥98% (HPLC),
Gatunek
human

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
D9190
DCEBIO, ≥98% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
1430000
Methylergonovine maleate, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Y0000776
Methylergometrine maleate, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Y0000777
Methylergometrine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
C4542
Cyclobenzaprine hydrochloride, ,
Gatunek
human
S006
Ketanserin (+)-tartrate salt, ≥97%, solid,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4501475
Anti-5-HT-2B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB2109002
Anti-HTR2B (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, canine, guinea pig, horse, human, mouse, pig
Zastosowanie
western blot
HPA012867
Anti-HTR2B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
SAB4501476
Anti-HTR2B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
western blot
SAB1403953
Monoclonal Anti-HTR2B antibody produced in mouse, clone 4F3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
M2525
Mianserin hydrochloride, ,
Gatunek
human
T3146
Trimipramine maleate salt, ≥98% (TLC), powder,
Gatunek
human
Z101
Zimelidine dihydrochloride, solid,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
N7261
Nortriptyline hydrochloride, ≥98% (HPLC), powder,
Gatunek
human
A129
Amoxapine, ,
Gatunek
human
F1553
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Gatunek
human
F1678
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Gatunek
human
S6319
Sertraline hydrochloride, ≥98% (HPLC),
Gatunek
human

Small Molecule - Metabolite

Numer produktu
Opis
Gatunek
H8876
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
M8046
Mifepristone, ≥98%,
Gatunek
human, mouse, rat
C6305
Clozapine, ,
Gatunek
human, rat

Small Molecule - Precursor

Numer produktu
Opis
Gatunek
H9772
5-Hydroxy-L-tryptophan, powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU052881
MISSION® esiRNA, targeting human HTR2B,
Gatunek
human