ML0010

TCA Cycle Metabolite Library

• Synonym(s): Kreb′s Cycle Metabolite Library
• NACRES: NA.25
• UNSPSC Code: 41116107

Properties

• Quality Level: 200
• application(s): advanced drug delivery
• storage temp.: −20°C

Description

Application

• Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients Using a Multiplatform Mass Spectrometry-Based Metabolomics Approach.: This study utilizes an advanced metabolomics approach to understand mitochondrial dysfunction in long COVID patients, highlighting the application of the TCA Cycle Metabolite Library for in-depth biological analysis (Martinez et al., 2024).


• OGDH and Bcl-xL loss causes synthetic lethality in glioblastoma.: This research explores the critical interactions in metabolic pathways, particularly the TCA cycle, affecting glioblastoma′s cellular metabolism and identifying potential therapeutic targets (Nguyen et al., 2024).


• The interactions and biological pathways among metabolomics products of patients with coronary heart disease.: Demonstrates how metabolomics, including TCA cycle metabolites, can reveal complex biochemical pathways in coronary heart disease, offering insights into potential interventions (Chu et al., 2024).


• Reduction in creatine metabolites in macrophages exposed to small molecule analogues of the anti-inflammatory parasitic worm product ES-62.: Investigates the impact of altered TCA cycle metabolites on macrophage biochemistry, providing a foundation for therapeutic research (Alanazi et al., 2024).


• In-vivo tracking of deuterium metabolism in mouse organs using LC-MS/MS.: This study applies cutting-edge analytical techniques to trace metabolic pathways in vivo, including key TCA cycle intermediates, which could be pivotal for clinical metabolic research (Kasarla et al., 2024).

Preparation Note

All components are directly water soluble at ≥ 50 mg/ml.

Other Notes

Contains 10 mg each of TCA cycle metabolite standards packaged individually.

Kit Components Also Available Separately

• A2056

  Acetyl coenzyme A trisodium salt, ≥93% (HPLC), powder 10 mg

  SDS
• C7129

  Citric acid monohydrate, reagent grade, ≥98% (GC/titration) 10 mg

  SDS
• F1506

  Sodium fumarate dibasic, ≥99% 10 mg

  SDS
• M1000

  L-(−)-Malic acid, ≥95% (titration) 10 mg

  SDS
• O4126

  Oxaloacetic acid, ≥97% (HPLC) 10 mg

  SDS
• P2256

  Sodium pyruvate, ReagentPlus^®, ≥99% 10 mg

  SDS
• S1129

  Succinyl coenzyme A sodium salt, ≥85% 10 mg

  SDS

See All (9)

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H317,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• wgk: WGK 3