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T0875

Sodium taurodeoxycholate hydrate

≥95% (HPLC)

Synonym(s):

2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate

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About This Item

Linear Formula:
C26H44NO6SNa · xH2O
CAS Number:
Molecular Weight:
521.69 (anhydrous basis)
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3901204
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description

anionic

Quality Level

assay

≥95% (HPLC)

mol wt

micellar avg mol wt 3100

aggregation number

6

CMC

1-4 mM (20-25°C)

application(s)

sample preservation

Application

Bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins.
Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. [1] It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures. [2]

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This Item
T9034T0557T4009
assay

≥95% (HPLC)

assay

≥95% (HPLC)

assay

≥97% (TLC)

assay

≥95% (HPLC)

aggregation number

6

aggregation number

4

aggregation number

6

aggregation number

4

application(s)

sample preservation

application(s)

detection

application(s)

-

application(s)

-

description

anionic

description

anionic

description

anionic

description

anionic

CMC

1-4 mM (20-25°C)

CMC

3-11 mM (20-25°C)

CMC

1-4 mM (20-25°C)

CMC

3-11 mM (20-25°C)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Related Content

Product Information Sheet


Barbara Orioni et al.
The journal of physical chemistry. B, 110(24), 12129-12140 (2006-06-28)
Mixtures containing water, bovine serum albumin (BSA), and sodium taurodeoxycholate (NaTDC), a component of the bile in mammals, have been investigated in a wide range of composition and pH. Depending on the concentration of both solutes and the pH, solutions
Jing-Yi Ye et al.
International journal of nanomedicine, 15, 6503-6518 (2020-09-15)
A non-lipolysis nanoemulsion (NNE) was designed to reduce the first-pass metabolism of raloxifene (RAL) by intestinal UDP-glucuronosyltransferases (UGTs) for increasing the oral absorption of RAL, coupled with in vitro and in vivo studies. In vitro stability of NNE was evaluated
Monalisa Mohapatra et al.
Langmuir : the ACS journal of surfaces and colloids, 27(22), 13461-13467 (2011-10-07)
The interaction of submicellar concentrations of various physiologically important unconjugated [sodium deoxycholate (NaDC), sodium cholate (NaC)] and conjugated [sodium glycodeoxycholate (NaGDC), sodium glycocholate (NaGC), sodium taurodeoxycholate (NaTDC), sodium taurocholate (NaTC)] bile salts with dipalmitoylphosphatidylcholine (DPPC) and dimyristoylphosphatidylcholine (DMPC) small unilamellar



Global Trade Item Number

SKUGTIN
T0875-50G04061837335952
T0875-5G04061837335969
T0875-25G04061837335945
T0875-1G04061837335938
T0875-100G04061837335839

Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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