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About This Item
Empirical Formula (Hill Notation):
C12H9F3N2O2
CAS Number:
Molecular Weight:
270.21
UNSPSC Code:
12352200
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Pricing and availability is not currently available.
Product Name
Teriflunomide, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
−20°C
InChI
1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
InChI key
UTNUDOFZCWSZMS-YFHOEESVSA-N
Application
Teriflunomide has been used as a dihydroorotate dehydrogenase (DHODH) inhibitor.[1]
Biochem/physiol Actions
Teriflunomide is an orally available anti-inflammatory immunomodulator.
Teriflunomide is an orally available anti-inflammatory immunomodulator. It blocks the activity of dihydroorotate dehydrogenase, preventing pyrimidine synthesis and T and B cell proliferation and function. Teriflunomide has been used to treat rheumatoid arthritis and was recently approved for multiple sclerosis.
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This Item | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay - | assay - | assay ≥98% (HPLC) |
| form powder | form - | form - | form powder |
| Quality Level 100 | Quality Level - | Quality Level - | Quality Level 100 |
| storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. room temp |
| solubility DMSO: 5 mg/mL, clear (warmed) | solubility - | solubility - | solubility DMSO: 25 mg/mL, clear |
| color white to beige | color - | color - | color white to beige |
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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