Long term stabilty studies of this material in solution have not been conducted. However, product 15861, Cobalt Chloride Solution, 0.1M, is stable for at least 1 year when stored at 2-8°C.
C8661
Cobalt(II) chloride hexahydrate
BioReagent, suitable for cell culture, suitable for insect cell culture
Synonym(s):
Cobaltous chloride hexahydrate
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About This Item
Linear Formula:
CoCl2 · 6H2O
CAS Number:
Molecular Weight:
237.93
NACRES:
NA.71
PubChem Substance ID:
UNSPSC Code:
12352207
EC Number:
231-589-4
MDL number:
Form:
powder
Pricing and availability is not currently available.
vapor pressure
40 mmHg ( 0 °C)
Quality Segment
product line
BioReagent
form
powder
technique(s)
cell culture | insect: suitable, cell culture | mammalian: suitable
SMILES string
O.O.O.O.O.O.Cl[Co]Cl
InChI
1S/2ClH.Co.6H2O/h2*1H;;6*1H2/q;;+2;;;;;;/p-2
InChI key
GFHNAMRJFCEERV-UHFFFAOYSA-L
Application
- Synthesis, Characterization, and Biological Activities of Novel Vanadium(IV) and Cobalt(II) Complexes: Investigates the synthesis of novel cobalt(II) complexes and their potential biological applications, particularly emphasizing their bioactive properties in various cellular models (Damena T, Zeleke D, Desalegn T, et al. 2022. ACS Omega).
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This Item | |||
|---|---|---|---|
| form powder | form powder | form solid | form crystals or chunks |
| Quality Level 300 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| vapor pressure 40 mmHg ( 0 °C) | vapor pressure 40 mmHg ( 0 °C) | vapor pressure 40 mmHg ( 0 °C) | vapor pressure 40 mmHg ( 0 °C) |
| technique(s) cell culture | insect: suitable, cell culture | mammalian: suitable | technique(s) cell culture | plant: suitable | technique(s) - | technique(s) - |
| product line BioReagent | product line - | product line - | product line - |
cell culture trace element, trace elements | cell culture trace element, trace elements | - | - |
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Danger
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B Inhalation - Eye Dam. 1 - Muta. 2 - Repr. 1B - Resp. Sens. 1 - Skin Sens. 1
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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According to the product specification sheet, Cobalt (II) Chloride Hexahydrate is soluble in water at a final concentration of 100mg/mL. What is the storage temperature of this aqueous solution?
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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Can C8661 be used in normoxia to induce hypoxia?
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CoCl2 is generally known to replace Fe2+ that binds to prolyl hydroxylase (PHD), which degrades hypoxia-inducible factor‑1α (HIF-1a) under normoxic conditions. This binding blocks the activity of PHD and subsequently upregulates the level of HIF-1a to simulate hypoxic conditions.
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