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A6500

Acetylcholine bromide

≥99%

Synonym(s):

ACh

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About This Item

Linear Formula:
(CH3)3N(Br)CH2CH2OCOCH3
CAS Number:
66-23-9
Molecular Weight:
226.11
UNSPSC Code:
51151519
NACRES:
NA.25
PubChem Substance ID:
24891093
EC Number:
200-622-4
Beilstein/REAXYS Number:
3572117
MDL number:
MFCD00011814
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Quality Level

100

assay

≥99%

form

powder

mp

140-143 °C (lit.)

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

storage temp.

−20°C

SMILES string

[Br-].CC(=O)OCC[N+](C)(C)C

InChI

1S/C7H16NO2.BrH/c1-7(9)10-6-5-8(2,3)4;/h5-6H2,1-4H3;1H/q+1;/p-1

InChI key

ZEHGKSPCAMLJDC-UHFFFAOYSA-M

Gene Information

human ... CHRM3(1131)

Application

Acetylcholine is an endogenous neurotransmitter at cholinergic synapses that amplifies action potential of the sarcolemma thereby inducing muscle contractions. Acetylcholine bromide is used as an acetylcholine receptor agonist to identify, characterize and differentiate among types of cholinergic receptors. Acetylcholine bromide is used as an inhibitor to identify and characterize natural and mutated butyrylcholinesterase(s).

Biochem/physiol Actions

Endogenous neurotransmitter at cholinergic synapses; amplifies action potential of the sarcolemma thereby inducing muscle contractions.

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Acetylcholine bromide ≥99%

Sigma-Aldrich

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Acetylcholine bromide

Acetylcholine chloride pkg of 150 mg (per vial)

Sigma-Aldrich

A9101

Acetylcholine chloride

Acetylcholine chloride ≥99% (TLC)

Sigma-Aldrich

A6625

Acetylcholine chloride

Acetylcholine chloride suitable for cell culture

Sigma-Aldrich

A2661

Acetylcholine chloride

assay

≥99%

assay

≥99% (TLC)

assay

≥99% (TLC)

assay

~99%

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

H2O: soluble

solubility

H2O: 100 mg/mL

solubility

water: 100 mg/mL, clear, colorless

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

form

powder

form

powder or crystals

form

-

form

powder

storage temp.

−20°C

storage temp.

room temp

storage temp.

-

storage temp.

room temp

Gene Information

human ... CHRM3(1131)

Gene Information

human ... CHRM3(1131)

Gene Information

human ... CHRM3(1131)

Gene Information

human ... CHRM3(1131)

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCV2188
MKCT0858
MKCP9464
MKCL2782
MKCJ0770

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Scott A Hollingsworth et al.
Nature communications, 10(1), 3289-3289 (2019-07-25)
Allosteric modulators are highly desirable as drugs, particularly for G-protein-coupled receptor (GPCR) targets, because allosteric drugs can achieve selectivity between closely related receptors. The mechanisms by which allosteric modulators achieve selectivity remain elusive, however, particularly given recent structures that reveal
Carmela Nacci et al.
Vascular pharmacology, 87, 83-91 (2016-08-28)
Increased TNFα-mediated JNK signaling in the perivascular adipose tissue (PVAT) may contribute to the pathogenesis of vascular complications in T1DM by reducing adiponectin (Ad) synthesis and therefore impairing Ad-mediated activity in the contiguous blood vessel system. We evaluated whether in
Sonia Donzelli et al.
Scientific reports, 7(1), 9938-9938 (2017-09-01)
Despite the mechanisms for endogenous nitroxyl (HNO) production and action being incompletely understood, pharmacological donors show broad therapeutic promise and are in clinical trials. Mass spectrometry and site-directed mutagenesis showed that chemically distinct HNO donors 1-nitrosocyclohexyl acetate or Angeli's salt
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Global Trade Item Number

SKUGTIN
A6500-100G04061835515738

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