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E1625

Elastin from bovine neck ligament

powder

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About This Item

CAS Number:
UNSPSC Code:
12352202
NACRES:
NA.61
EC Number:
232-701-4
MDL number:
Form:
powder
Biological source:
bovine neck ligament
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biological source

bovine neck ligament

Quality Segment

form

powder

UniProt accession no.

storage temp.

2-8°C

SMILES string

N1([C@@H](CCC1)C(=O)NC)C(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CC(C)C)[C@H](CC)C)C(C)C

InChI

1S/C27H48N6O6/c1-9-17(6)23(32-24(36)19(13-15(2)3)30-18(7)34)26(38)29-14-21(35)31-22(16(4)5)27(39)33-12-10-11-20(33)25(37)28-8/h15-17,19-20,22-23H,9-14H2,1-8H3,(H,28,37)(H,29,38)(H,30,34)(H,31,35)(H,32,36)/t17-,19-,20-,22-,23-/m0/s1

InChI key

DPUYCSDGMSDKKV-MKBYFEBXSA-N

Gene Information

cow ... ELN(280781)

Application

Elastin is a structural protein which has been used in studies of Chronic obstructive pulmonary disease (COPD). It may be used to investigate why there is a lack of repair for these proteins in patients with COPD.
Highly stable and hemocompatible protein now finding use in construction of biomaterials as a result of several strategies for its solubilization.

Biochem/physiol Actions

Protein responsible for the elasticity of many tissues. It is especially important in blood vessels, where it comprises about 50% of the dry tissue weight.

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This Item
E6527L6385T9145
biological source

bovine neck ligament

biological source

bovine neck ligament

biological source

bovine milk

biological source

bovine thyroid

form

powder

form

salt-free, lyophilized powder

form

powder

form

powder

Gene Information

cow ... ELN(280781)

Gene Information

cow ... ELN(280781)

Gene Information

cow ... LALBA(281894)

Gene Information

cow ... TG(280706)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

UniProt accession no.

P04985

UniProt accession no.

P04985

UniProt accession no.

P00711

UniProt accession no.

P01267

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Global Trade Item Number

SKUGTIN
E1625-10G04061833601990
E1625-5G04061833602003

Questions

1–2 of 2 Questions  
  1. What is the density (g/cm^3) of the elastin?

    1 answer
    1. The density of this product has not been determined.

      Helpful?

  2. Hello, I was wondering if you can recommend any procedures for dissolving the powder? I have tried in 0.2M Tris pH8.8 at 10mg/mL, as recommend in literature without success.

    1 answer
    1. This product is tested for solubility at 10mg/mL in 0.2M Tris, pH 8.8, resulting in a turbid solution. A clear solution has not been obtained. A further purified, salt-free version of this material, product E6527, produces a clear to hazy solution in water at 10mg/mL. Please see the link below to review a sample or lot-specific Certificate of Analysis for this item:
      https://www.sigmaaldrich.com/product/sigma/e6527#product-documentation

      Helpful?

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