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About This Item
Empirical Formula (Hill Notation):
C26H43NO5
CAS Number:
Molecular Weight:
449.62
UNSPSC Code:
12161900
PubChem Substance ID:
NACRES:
NA.25
MDL number:
Pricing and availability is not currently available.
biological source
synthetic
Quality Segment
assay
≥96.0% (TLC)
form
powder
functional group
carboxylic acid
InChI
1S/C26H43NO5/c1-15(4-7-22(30)27-14-23(31)32)18-5-6-19-24-20(9-11-26(18,19)3)25(2)10-8-17(28)12-16(25)13-21(24)29/h15-21,24,28-29H,4-14H2,1-3H3,(H,27,30)(H,31,32)/t15-,16+,17-,18-,19+,20+,21+,24+,25+,26-/m1/s1
InChI key
GHCZAUBVMUEKKP-XROMFQGDSA-N
Application
- Glycoursodeoxycholic Acid Alleviates Arterial Thrombosis via Suppressing Diacylglycerol Kinases Activity in Platelet.: Highlights the therapeutic potential of Glycoursodeoxycholic acid in alleviating arterial thrombosis by inhibiting diacylglycerol kinase activity in platelets (Yang et al., 2024).
Biochem/physiol Actions
Secondary bile acid derived from acyl glycine. Glycoursodeoxycholic Acid (GUDCA) is reported to have cytoprotective and anti-inflammatory effects.
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This Item | |||
|---|---|---|---|
| form powder | form powder | form powder | form - |
| assay ≥96.0% (TLC) | assay ≥99% | assay ≥97% (HPLC) | assay ≥98% |
| biological source synthetic | biological source - | biological source synthetic | biological source - |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| functional group carboxylic acid | functional group - | functional group amide | functional group - |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Kazuya Maeda et al.
Molecular pharmaceutics, 3(1), 70-77 (2006-05-12)
Ursodeoxycholate (UDCA) is widely used for the treatment of cholestatic liver disease. After oral administration, UDCA is absorbed, taken up efficiently by hepatocytes, and conjugated mainly with glycine to form glycoursodeoxycholate (GUDC) or partly with taurine to form tauroursodeoxycholate (TUDC)
Sandra L Silva et al.
Neuropharmacology, 62(7), 2398-2408 (2012-03-01)
Neuronal oxidative damage and cell death by unconjugated bilirubin (UCB) showed to be mediated by overstimulation of glutamate receptors and nitric oxide (NO) production, which was abrogated by the bile acid glycoursodeoxycholic acid (GUDCA). Microglia, a crucial mediator of CNS
Jingyu Yan et al.
Scientific reports, 7(1), 4211-4211 (2017-06-25)
Cholestasis is a clinical disorder defined as an impairment of bile flow, and that leads to toxic bile acid (BA) accumulation in hepatocytes. Here, we investigated the hepatoprotective effect of Yinchenhaotang (YCHT), a well-known formulae for the treatment of jaundice
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 06863-1G | 04061826268872 |



