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Xylene Substitute

Name: Xylene Substitute
Brand: SIGMA

Synonym(s):

for microscopy

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About This Item

UNSPSC Code:

12171500

EC Number:

265-068-8

NACRES:

NA.47

Form:

solution

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Properties

form

solution

greener alternative product characteristics

Designing Safer Chemicals
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

density

0.723 g/cm³

application(s)

hematology
histology

greener alternative category

, Aligned

storage temp.

2-8°C

Description

General description

Compatible with all tissue processors. May not be compatible with all permanent mounting media.

Application

Xylene Substitute has been used to dewax or de-paraffinize the specimen sections after the staining process.We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has Inherently Safer Chemistry, compared to the standard use of formalin for tissue processing. For more information see www.sigmaaldrich.com/catalog/papers/19608083.

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This Item	78475	1.09843	PHR1313
Sigma-Aldrich A5597 Xylene Substitute	Sigma-Aldrich 78475 Xylene Substitute	Sigma-Aldrich 1.09843 Neo-Clear^™ Xylene Substitute	Supelco PHR1313 m-Xylene
form solution	form liquid	form liquid	form -
storage temp. 2-8°C	storage temp. -	storage temp. 15-25°C	storage temp. 2-30°C
density 0.723 g/cm³	density 0.75 g/mL at 20 °C	density 0.78-0.795 g/cm³ at 20 °C	density 0.868 g/mL at 25 °C (lit.)
sustainability Greener Alternative Product	sustainability -	sustainability Greener Alternative Product	sustainability -
greener alternative product characteristics Designing Safer Chemicals Learn more about the Principles of Green Chemistry.	greener alternative product characteristics -	greener alternative product characteristics Safer Solvents and Auxiliaries Learn more about the Principles of Green Chemistry.	greener alternative product characteristics -
greener alternative category , Aligned	greener alternative category -	greener alternative category Aligned	greener alternative category -

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pictograms

GHS02,GHS08

signalword

Danger

hcodes

H225,H304

pcodes

P210 - P233 - P240 - P241 - P301 + P310 - P331

Hazard Classifications

Asp. Tox. 1 - Flam. Liq. 2

Storage Class

3 - Flammable liquids

flash_point_f

63.0 °F - closed cup

flash_point_c

17.2 °C - closed cup

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Histology without xylene.

René J Buesa et al.

Annals of diagnostic pathology, 13(4), 246-256 (2009-07-18)

After the hazardous effects of xylene became indisputable in the 1970s, many potential substitutes became available, some with as many if not more hazards. This article discusses the inadequacy of 5 vegetable oils as substitutes, as well as the characteristics

Multiplex protein-specific microscopy with ultraviolet surface excitation.

Jiaming Guo et al.

Biomedical optics express, 11(1), 99-108 (2020-02-06)

Immunohistochemical techniques, such as immunofluorescence (IF) staining, enable microscopic imaging of local protein expression within tissue samples. Molecular profiling enabled by IF is critical to understanding pathogenesis and is often involved in complex diagnoses. A recent innovation, known as microscopy

Physical activity prevents acute inflammation in a gout model by downregulation of TLR2 on circulating neutrophils as well as inhibition of serum CXCL1 and is associated with decreased pain and inflammation in gout patients.

Kyle Jablonski et al.

PloS one, 15(10), e0237520-e0237520 (2020-10-02)

Gout is the most prevalent inflammatory arthritis. To study the effects of regular physical activity and exercise intensity on inflammation and clinical outcome, we examined inflammatory pathogenesis in an acute model of murine gout and analyzed human gout patient clinical

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Global Trade Item Number

SKU	GTIN
A5597-4X1GAL	04061838203632
A5597-1GAL	04061833376072

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