ABC442

Anti-Cathepsin Z Antibody

from rabbit, purified by affinity chromatography

• Synonym(s): Cathepsin Z, Cathepsin P, Cathepsin X
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: -

Properties

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human
• technique(s): western blot: suitable
• NCBI accession no.: NP_001327
• UniProt accession no.: Q9UBR2
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... CTSZ(1522)

Description

General description

Cathepsin Z, also known as Cathepsin P, Cathepsin X, and encoded by the gene name CTSZ, is a member of the the peptidase C1 family. Cathepsin Z is a lysosomal cysteine proteinase that exhibits both carboxy-monopeptidase and carboxy-dipeptidase activities. Cathepsin Z is expressed ubiquitously in cancer cell lines and primary tumors and, like other members of this family, may be involved in tumorigenesis. At least two transcript variants of this gene have been found, but the full-length nature of only one of them has been determined.

~33 kDa observed. (Pungecar, J., et al. (2000). PMID: 10653163)

Immunogen

Epitope: Near C-terminus

KLH-conjugated linear peptide corresponding to human Cathepsin Z near the C-terminus.

Application

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

This Anti-Cathepsin Z antibody is validated for use in Western Blotting for the detection of Cathepsin Z.

Physical form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected Cathepsin Z in 10 µg of human liver tissue lysate.

Other Notes

Concentration: Please refer to lot specific datasheet.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable