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Galantamine hydrobromide

Name: Galantamine hydrobromide
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Galanthamine hydrobromide

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About This Item

Empirical Formula (Hill Notation):

C₁₇H₂₁NO₃ · HBr

CAS Number:

1953-04-4

Molecular Weight:

368.27

UNSPSC Code:

41116107

NACRES:

NA.24

EC Number:

217-780-5

MDL number:

MFCD26142877

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Properties

grade

pharmaceutical primary standard

API family

galantamine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

[H][C@]1(O2)C[C@@H](O)C=C[C@@]13C4=C2C(OC)=CC=C4CN(C)CC3.Br

InChI

1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1

InChI key

QORVDGQLPPAFRS-XPSHAMGMSA-N

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Galantamine hydrobromide USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

Galantamine Extended-Release Capsules
Galantamine Hydrobromide
Galantamine Oral Solution
Galantamine Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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1 of 1

This Item	Y0001279	PHR1623	Y0001191
USP 1287755 Galantamine hydrobromide	Y0001279 Galantamine hydrobromide	Supelco PHR1623 Galantamine Hydrobromide	Y0001191 Galantamine synthetic for system suitability
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename -	manufacturer/tradename EDQM
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade certified reference material, pharmaceutical secondary standard	grade pharmaceutical primary standard
format neat	format neat	format neat	format neat
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)
API family galantamine	API family galantamine	API family galantamine	API family galantamine

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pictograms

GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

Not applicable

flash_point_c

Not applicable

pcodes

P264 - P270 - P301 + P310 - P405 - P501

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Certificates of Analysis (COA)

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Hyperglycemia induces memory impairment linked to increased acetylcholinesterase activity in zebrafish (Danio rerio).

Katiucia Marques Capiotti et al.

Behavioural brain research, 274, 319-325 (2014-08-27)

Diabetes mellitus, which causes hyperglycemia, affects the central nervous system and can impairs cognitive functions, such as memory. The aim of this study was to investigate the effects of hyperglycemia on memory as well as on the activity of acethylcholinesterase.

Flow-through enzyme immobilized amperometric detector for the rapid screening of acetylcholinesterase inhibitors by flow injection analysis.

Marie Vandeput et al.

Journal of pharmaceutical and biomedical analysis, 102, 267-275 (2014-12-03)

A commercially available thin-layer flow-through amperometric detector, with the sensing block customized in an original design, was applied to the screening of drug compounds known as acetylcholinesterase (AChE) inhibitors. AChE from electric eel was covalently immobilized onto a cysteamine modified

Systematic evaluation of commercially available ultra-high performance liquid chromatography columns for drug metabolite profiling: optimization of chromatographic peak capacity.

Anne-Charlotte Dubbelman et al.

Journal of chromatography. A, 1374, 122-133 (2014-12-02)

The present study investigated the practical use of modern ultra-high performance liquid chromatography (UHPLC) separation techniques for drug metabolite profiling, aiming to develop a widely applicable, high-throughput, easy-to-use chromatographic method, with a high chromatographic resolution to accommodate simultaneous qualitative and

Global Trade Item Number

SKU	GTIN
1287755-200MG	04061838725950

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