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Betahistine hydrochloride

Name: Betahistine hydrochloride
Brand: USP

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Betahistine dihydrochloride, Methyl[2-(2-pyridyl)ethyl]amine dihydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₂N₂ · 2HCl

CAS Number:

5579-84-0

Molecular Weight:

209.12

NACRES:

NA.24

PubChem Substance ID:

329748927

UNSPSC Code:

41116107

MDL number:

MFCD00012813

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Properties

grade

pharmaceutical primary standard

API family

betahistine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cl.CNCCc1ccccn1

InChI

1S/C8H12N2.2ClH/c1-9-7-5-8-4-2-3-6-10-8;;/h2-4,6,9H,5,7H2,1H3;2*1H

InChI key

XVDFMHARQUBJRE-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269), HRH3(11255)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betahistine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

Other Notes

Sales restrictions may apply.

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1 of 1

This Item	Y0000391	BP824	1526007
USP 1065618 Betahistine hydrochloride	Y0000391 Betahistine dihydrochloride	BP824 Betahistine dihydrochloride	USP 1526007 Phenoxybenzamine hydrochloride
grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard	grade pharmaceutical primary standard
manufacturer/tradename USP	manufacturer/tradename EDQM	manufacturer/tradename BP	manufacturer/tradename USP
application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)
format neat	format neat	format neat	format neat
Gene Information human ... HRH1(3269), HRH3(11255)	Gene Information human ... HRH1(3269), HRH3(11255)	Gene Information human ... HRH1(3269), HRH3(11255)	Gene Information human ... ADRA1A(148), ADRA1B(147), ADRA1D(146), ADRA2A(150), ADRA2B(151), ADRA2C(152)
API family betahistine	API family betahistine	API family betahistine	API family phenoxybenzamine

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Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Differential thermodynamic driving force of first- and second-generation antihistamines to determine their binding affinity for human H1 receptors.

Shigeru Hishinuma et al.

Biochemical pharmacology, 91(2), 231-241 (2014-07-30)

Differential binding sites for first- and second-generation antihistamines were indicated on the basis of the crystal structure of human histamine H1 receptors. In this study, we evaluated differences between the thermodynamic driving forces of first- and second-generation antihistamines for human

Global Trade Item Number

SKU	GTIN
1065618-200MG	04061838674180

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