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U7129

Sigma-Aldrich

Urea solution

40 % (w/v) in H2O

Synonym(s):

Carbamide, Carbonyldiamide

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About This Item

Linear Formula:
NH2CONH2
CAS Number:
57-13-6
Molecular Weight:
60.06
Beilstein:
635724
MDL number:
MFCD00008022
UNSPSC Code:
12352111
PubChem Substance ID:
24900664
NACRES:
NA.75

sterility

non-sterile; sterile-filtered

Quality Level

100

contains

0.1% benzoic acid as preservative

packaging

vial of 5 mL

concentration

40 % (w/v) in H2O

storage temp.

2-8°C

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

Gene Information

human ... CA1(759) , CA2(760) , EPHX2(2053)
mouse ... Ephx2(13850)
rat ... Ppm1a(24666)

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Application

Recommended for the detection of urease activity.

Biochem/physiol Actions

Urea solution is primarily used for protein denaturation. It also increases solubility of hydrocarbons and reduce micelle formation. Urea solution at high concentration leads to the destabilization of amyloid β16−22 oligomers.

Preparation Note

Warm the refrigerated 40% urea solution to room temperature. Aseptically add 5 mL to 95 mL of sterile molten Urea Agar Base (Christensen). Mix well and dispense in sterile tubes.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Aqueous urea solutions: structure, energetics, and urea aggregation
Stumpe MC, et al.
The Journal of Physical Chemistry B, 111(22), 6220-6228 (2007)
L Li et al.
Cell death and differentiation, 22(7), 1081-1093 (2014-12-20)
P53 is critically important in preventing oncogenesis but its role in inflammation in general and in the function of inflammatory macrophages in particular is not clear. Here, we show that bone marrow-derived macrophages exhibit endogenous p53 activity, which is increased
A mechanically and electrically self-healing supercapacitor.
Hua Wang et al.
Advanced materials (Deerfield Beach, Fla.), 26(22), 3638-3643 (2014-02-21)
G L French et al.
Lancet (London, England), 2(8551), 117-119 (1987-07-18)
Tuberculostearic acid, a structural component of Mycobacterium tuberculosis, was identified by gas chromatography/mass spectrometry with selected ion monitoring in cerebrospinal fluid (CSF) from 13 patients with proven and 8 out of 9 patients with suspected tuberculous meningitis; the negative result
Marco Benevento et al.
Nature communications, 5, 5613-5613 (2014-12-11)
The ectopic expression of Oct4, Klf4, c-Myc and Sox2 (OKMS) transcription factors allows reprogramming of somatic cells into induced pluripotent stem cells (iPSCs). The reprogramming process, which involves a complex network of molecular events, is not yet fully characterized. Here
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