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U2875

Uric acid sodium salt

Synonym(s):

2,6,8-Trihydroxypurine, Sodium acid urate

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About This Item

Linear Formula:
C5H3N4O3Na
CAS Number:
Molecular Weight:
190.09
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
214-838-1
MDL number:
Assay:
11.0-13.0% anhydrous basis (Sodium, ICP)
Biological source:
microbial, synthetic
Form:
powder
Solubility:
1 M NaOH: 25 mg/mL, clear, colorless to faintly yellow
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Quality Level

biological source

microbial, synthetic

assay

11.0-13.0% anhydrous basis (Sodium, ICP)

form

powder

solubility

1 M NaOH: 25 mg/mL, clear, colorless to faintly yellow

SMILES string

[Na].O=C1NC(=O)C2=C(N1)NC(=O)N2

InChI

1S/C5H4N4O3.Na.H/c10-3-1-2(7-4(11)6-1)8-5(12)9-3;;/h(H4,6,7,8,9,10,11,12);;

InChI key

IHMJZGFANDMEJM-UHFFFAOYSA-N

Application

Uric acid sodium salt has been used in isotonic solution of NaCl dose titration study. It has been used as a suspension in NaCl for intra-articular administration to experimental animals to induce synovitis.

Biochem/physiol Actions

Sodium urate is the sodium salt of uric acid. In gout, it is observed in synovial fluid. Sodium urate has been shown to precipitate calcium oxalate from urine. It is also known to reverse the inhibitory effects of reactive oxygen and nitrogen metabolites on gelatinase A activity. Excess sodium urate in soft tissues results in a condition referred to as tophi.

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1 of 1

This Item
U2625U0881NIST913B
biological source

microbial, synthetic

biological source

-

biological source

animal (seabird feces (guano))

biological source

-

Quality Level

200

Quality Level

100, 200

Quality Level

200

Quality Level

100

form

powder

form

crystalline

form

powder

form

crystalline (solid)

assay

11.0-13.0% anhydrous basis (Sodium, ICP)

assay

≥99%

assay

≥99% (HPLC)

assay

-

solubility

1 M NaOH: 25 mg/mL, clear, colorless to faintly yellow

solubility

-

solubility

1 M NaOH: soluble 50 mg/mL, clear, faintly yellow

solubility

-


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Related Content

Product Information Sheet


Jieru Han et al.
Journal of natural medicines, 75(1), 37-47 (2020-08-08)
Monosodium urate (MSU)-mediated inflammation is closely related to gouty arthritis (GA). Dioscin, an active ingredient, has been reported to possess anti-inflammatory property. Nevertheless, the role of dioscin in GA and the underlying mechanism have not been fully understood. In the
Preferential accumulation of meloxicam in inflamed synovial joints of dogs
Johnston L and Narbe R
The Veterinary Record, vetrec-ve2011 (2012)
Linne & Ringsrud's Clinical Laboratory Science, 429-432 (2015)



Global Trade Item Number

SKUGTIN
U2875-25G04061837409417
U2875-100G04061833614327
U2875-5G04061837409424

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What's the Grade of this compound?

    1 answer
    1. This is a research grade Uric Acid Sodium Salt.

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