T2528

Terbutaline hemisulfate salt

β-adrenoceptor agonist

• Synonym(s): 2-t-Butylamino-1-(3,5-dihydroxyphenyl)ethanol, 5-[2-[(1,1-Dimethylethyl)amino]-1-hydroxyethyl]-1,3-benzenediol hemisulfate salt
• Linear Formula: C₁₂H₁₉NO₃ · 1/2H₂SO₄
• CAS Number: 23031-32-5
• Molecular Weight: 274.32
• NACRES: NA.77
• PubChem Substance ID: 24278729
• UNSPSC Code: 12352200
• EC Number: 245-386-3
• MDL number: MFCD00079584

Properties

• Product Name: Terbutaline hemisulfate salt,
• Quality Segment: 100
• solubility: H₂O: soluble 100 mg/mL, clear to slightly hazy, colorless to yellow
• originator: Novartis
• SMILES string: OS(O)(=O)=O.CC(C)(C)NCC(O)c1cc(O)cc(O)c1.CC(C)(C)NCC(O)c2cc(O)cc(O)c2
• InChI: 1S/2C12H19NO3.H2O4S/c2*1-12(2,3)13-7-11(16)8-4-9(14)6-10(15)5-8;1-5(2,3)4/h2*4-6,11,13-16H,7H2,1-3H3;(H2,1,2,3,4)
• InChI key: KFVSLSTULZVNPG-UHFFFAOYSA-N
• Gene Information: human ... ADRB1(153), ADRB2(154), ADRB3(155)

Description

Application

Terbutaline hemisulfate has been used as a reference standard for the determination of β agonist residues in meat⁴. It has also been used as a standard for developing LC-MS-MS based techniques for the analysis of veterinary drugs⁵.

Biochem/physiol Actions

Terbutaline is a β-adrenoceptor agonist and is known to function as a bronchodilator. Studies have reported that terbutaline is potent inhibitor of premature labor⁶.

Features and Benefits

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Preparation Note

Terbutaline hemisulfate salt dissolves in water at 100 mg/ml to yield a colorless to yellow, clear to slightly hazy solution.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H361,H370
• pcodes: P202 - P260 - P264 - P270 - P280 - P308 + P311
• Hazard Classifications: Repr. 2 - STOT SE 1
• target_organs: Cardio-vascular system
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges