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Pyridoxine hydrochloride

Name: Pyridoxine hydrochloride
Brand: SIGMA

BioReagent, suitable for cell culture, suitable for insect cell culture, suitable for plant cell culture

Synonym(s):

Adermine hydrochloride, PN HCl, Pyridoxol hydrochloride, Vitamin B₆ hydrochloride

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About This Item

Empirical Formula (Hill Notation):

C₈H₁₁NO₃ · HCl

CAS Number:

58-56-0

Molecular Weight:

205.64

NACRES:

NA.21

PubChem Substance ID:

24898752

eCl@ss:

34058008

UNSPSC Code:

12161900

EC Number:

200-386-2

MDL number:

MFCD00012807

Beilstein/REAXYS Number:

3632435

Pricing and availability is not currently available.

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Properties

product line

BioReagent

Quality Level

200

assay

≥98% (HPLC)

form

powder

mol wt

M_w 205.64 g/mol

technique(s)

cell culture | insect: suitable, cell culture | mammalian: suitable, cell culture | plant: suitable

color

white to off-white

mp

214-215 °C (lit.)

solubility

water: soluble 50 mg/mL, clear, colorless to faintly yellow

application(s)

agriculture

SMILES string

Cl[H].Cc1ncc(CO)c(CO)c1O

InChI

1S/C8H11NO3.ClH/c1-5-8(12)7(4-11)6(3-10)2-9-5;/h2,10-12H,3-4H2,1H3;1H

InChI key

ZUFQODAHGAHPFQ-UHFFFAOYSA-N

Description

General description

Pyridoxine is a water-soluble vitamin that exists in six forms called, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate, and pyridoxal 5′-phosphate.

Application

Pyridoxine hydrochloride has been used:

as a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies
as a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA
as a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity

Biochem/physiol Actions

Pyridoxine functions as an essential coenzyme for amino acid, carbohydrate, and lipid metabolism. Pyridoxine deficiency is associated with peripheral neuropathy, microcytic anemia, and electroencephalographic abnormalities. It is implicated in a wide range of biochemical reactions that affect cellular processes. Pyridoxine serves as an alternative to pyridoxal which can degrade in media.

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1 of 1

This Item	BP458	P4100000	1587001
Sigma-Aldrich P6280 Pyridoxine hydrochloride	BP458 Pyridoxine hydrochloride	P4100000 Pyridoxine hydrochloride	USP 1587001 Pyridoxine hydrochloride
technique(s) cell culture \| insect: suitable, cell culture \| plant: suitable, cell culture \| mammalian: suitable	technique(s) -	technique(s) gas chromatography (GC): suitable, liquid chromatography (LC): suitable	technique(s) -
assay ≥98% (HPLC)	assay -	assay -	assay -
form powder	form solid	form solid	form -
application(s) agriculture	application(s) pharmaceutical pharmaceutical small molecule	application(s) pharmaceutical (small molecule)	application(s) pharmaceutical (small molecule)
solubility water: soluble 50 mg/mL, clear, colorless to faintly yellow	solubility -	solubility -	solubility -
Quality Level 200	Quality Level -	Quality Level -	Quality Level -

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Explore all of our products under Pyridoxine hydrochloride

pictograms

GHS05

signalword

Danger

hcodes

H318

pcodes

P280 - P305 + P351 + P338

Hazard Classifications

Eye Dam. 1

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

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Activity of Pyrazinamide against Mycobacterium tuberculosis at Neutral pH in PZA-S1 Minimal Medium.

Wanliang Shi

Antibiotics (Basel, Switzerland), 10(8) (2021-08-28)

Susceptibility testing of tuberculosis (TB) drugs on Mycobacterium tuberculosis is essential for the rapid detection of strains resistant to the drugs, providing the patient with effective treatment, and preventing the spread of drug-resistant TB strains. Pyrazinamide (PZA) is one of

Uremic Toxin Lanthionine Interferes with the Transsulfuration Pathway, Angiogenetic Signaling and Increases Intracellular Calcium.

Carmela Vigorito et al.

International journal of molecular sciences, 20(9) (2019-05-11)

(1) The beneficial effects of hydrogen sulfide (H2S) on the cardiovascular and nervous system have recently been re-evaluated. It has been shown that lanthionine, a side product of H2S biosynthesis, previously used as a marker for H2S production, is dramatically

A teaching protocol demonstrating the use of EasyClone and CRISPR/Cas9 for metabolic engineering of Saccharomyces cerevisiae and Yarrowia lipolytica.

N Milne et al.

FEMS yeast research, 20(2) (2019-09-27)

We present a teaching protocol suitable for demonstrating the use of EasyClone and CRISPR/Cas9 for metabolic engineering of industrially relevant yeasts Saccharomyces cerevisiae and Yarrowia lipolytica, using β-carotene production as a case study. The protocol details all steps required to

View All Related Papers

Global Trade Item Number

SKU	GTIN
P6280-100G	04061834393238
P6280-25G	04061834393245
P6280-10G	04061835547944

Questions

1–2 of 2 Questions

Anonymous

10 months ago

How can I determine the shelf life / expiration / retest date of this product?

1 answer
1. Technical Support
  
  10 months ago
  
  If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
  For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
  For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
  For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf
  
  Helpful?
Anonymous

a year ago

How is shipping temperature determined? And how is it related to the product storage temperature?

1 answer
1. Technical Support
  
  a year ago
  
  Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
  
  Helpful?

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