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P5397

n-Propionyl coenzyme A lithium salt

≥85%

Synonym(s):

n-Propionyl CoA lithium salt

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About This Item

Empirical Formula (Hill Notation):
C24H40N7O17P3S
CAS Number:
Molecular Weight:
823.60
UNSPSC Code:
41106305
PubChem Substance ID:
NACRES:
NA.51
Form:
powder
Assay:
≥85%
Solubility:
H2O: soluble-50 mg/mL, clear, colorless
Biological source:
yeast
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biological source

yeast

Quality Level

assay

≥85%

form

powder

solubility

H2O: soluble-50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

[Li].[P](=O)(O[P](=O)(OCC([C@@H](O)C(=O)NCCC(=O)NCCSC(=O)CC)(C)C)O)(OC[C@H]1O[C@H]([C@@H]([C@@H]1O[P](=O)(O)O)O)[n]2c3ncnc(c3nc2)N)O

InChI

1S/C24H40N7O17P3S.Li/c1-4-15(33)52-8-7-26-14(32)5-6-27-22(36)19(35)24(2,3)10-45-51(42,43)48-50(40,41)44-9-13-18(47-49(37,38)39)17(34)23(46-13)31-12-30-16-20(25)28-11-29-21(16)31;/h11-13,17-19,23,34-35H,4-10H2,1-3H3,(H,26,32)(H,27,36)(H,40,41)(H,42,43)(H2,

InChI key

CXNLEKKSVXVZAF-IEQRABFGSA-N

General description

Propionyl-CoA is obtained as an end product of isoleucine, valine and methionine catabolism. It is an essential component for the methylaspartate cycle. Branched-chain amino acids and cholesterol also give rise to propionyl-CoA. Propionyl coenzyme A (CoA) is the coenzyme A derivative of propionic acid. Propionyl CoA is formed during the β-oxidation of odd-chain fatty acids.

Biochem/physiol Actions

Coenzyme A functions as an acyl group carrier, acetyl-CoA. Propionyl coenzyme A (Propionyl-CoA) may be used to characterize and study propionyl-coenzyme A carboxylase complexes found in bacteria. Propionyl-CoA may be used to study the specificity and kinetics of methylisocitrate lyase(s).

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This Item
B1638C6146I0383
solubility

H2O: soluble-50 mg/mL, clear, colorless

solubility

-

solubility

-

solubility

-

assay

≥85%

assay

≥90%

assay

≥90% (HPLC)

assay

≥85%

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

biological source

yeast

biological source

-

biological source

-

biological source

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

powder

form

solid

form

powder

form

-


pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Production of 3-Hydroxypropionic Acid via the Propionyl-CoA Pathway Using Recombinant Escherichia coli Strains
Luo H, et al.
Testing, 11(5), e0156286-e0156286 (2016)
TetR family transcriptional regulator PccD negatively controls propionyl coenzyme A assimilation in Saccharopolyspora erythraea
Xu Z, et al.
Journal of Bacteriology, 199(20), e00281-e00217 (2017)
Atanas V Demirev et al.
Journal of microbiology (Seoul, Korea), 49(3), 407-412 (2011-07-01)
Acyl-CoA carboxylases (ACC) are involved in important primary or secondary metabolic pathways such as fatty acid and/or polyketides synthesis. In the 62 kb fragment of pccB gene locus of Streptomyces toxytricini producing a pancreatic inhibitor lipstatin, 3 distinct subunit genes



Global Trade Item Number

SKUGTIN
P5397-5MG04061834391647
P5397-25MG04061833264782
P5397-10MG04061833264775

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