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H6501

DL-β-Hydroxybutyric acid sodium salt

~98%, powder

Synonym(s):

(±)-3-Hydroxybutanoic acid sodium salt

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About This Item

Linear Formula:
C4H7O3Na
CAS Number:
Molecular Weight:
126.09
NACRES:
NA.83
PubChem Substance ID:
UNSPSC Code:
12352204
EC Number:
205-774-5
MDL number:
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Product Name

DL-β-Hydroxybutyric acid sodium salt, ~98%

assay

~98%

Quality Segment

form

powder

solubility

water: 1 g/10 mL, clear, colorless

storage temp.

2-8°C

SMILES string

[Na].CC(O)CC(O)=O

InChI

1S/C4H8O3.Na/c1-3(5)2-4(6)7;/h3,5H,2H2,1H3,(H,6,7);/q;+1/p-1

InChI key

NBPUSGBJDWCHKC-UHFFFAOYSA-M

Application

DL-β-Hydroxybutyric acid sodium salt has been used:
  • as a standard for quantifying blood plasma and milk β-hydroxybutyric acid in Danish Jersey cows
  • to investigate its anticonvulsant effects in epilepsy induced rats[1]
  • to induce hyperketonemia in Holstein dairy cows[2]

Biochem/physiol Actions

β-Hydroxybutyric acid is a ketone body present in the rumen epithelium of liver cells. Its interconversion to acetoacetate influences the acid-base balance and is coupled NADH generation from (nicotinamide adenine dinucleotide) NAD+, measured fluorimetrically. A high plasma level of β-hydroxybutyric acid is implicated in diabetic ketoacidosis. It traverses the blood-brain barrier as a monocarboxylic acid. β-Hydroxybutyric acid may play a protective role in dopaminergic neurodegeneration in Parkinson′s disease model. β-Hydroxybutyric acid is a ligand for G protein-coupled receptor(GPR109A) and favors inhibition of secretion, transcription and translation of growth hormone (GH) and prolactin (PRL) gene in cow anterior pituitary cells (DCAPCs).[3]

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This Item
K1875221511C4945
assay

~98%

assay

≥98% (titration)

assay

98%

assay

≥98%

solubility

water: 1 g/10 mL, clear, colorless

solubility

water: 100 mg/mL, clear, colorless

solubility

water: 1 g/10 mL, clear to slightly hazy, colorless

solubility

H2O: 0.5 M, clear, colorless

Quality Level

200

Quality Level

300

Quality Level

200

Quality Level

200

form

powder

form

powder

form

solid

form

powder

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

-

storage temp.

room temp


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Global Trade Item Number

SKUGTIN
H6501-5G04061833800966
H6501-25G04061833057827
H6501-100G04061833057810

Questions

  1. Bonjour,  Une fois avoir dilué le BHB  dans l'eau, est-il possible de congeler la solution ?  Merci d'avance

    1 answer
    1. The stability of this product in solution has not been evaluated. However, product MAK041 is a B-Hydroxybutyrate assay kit. This kit includes a B-Hysroxybutyrate standard solution at a concentration of 10 mM. The kit is stored at −20°C and has a warranty of 1 year from the date of shipment. Similar stability would be expected for the H6501, provided the stock solution is of similar concentration and aliquoted to avoid repeated freeze/thaw cycles.

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