H4126

Hydrocortisone 21-acetate

≥98% (HPLC), corticosteroid, powder

• Synonym(s): 11β,17α,21-Trihydroxy-4-pregnene-3,20-dione 21-acetate, 17-α-Hydroxycorticosterone acetate, 17-Hydroxycorticosterone 21-acetate, 21-Acetoxy-4-pregnene-11β,17α-diol-3,20-dione, 4-Pregnene-11β,17α,21-triol-3,20-dione 21-acetate
• Empirical Formula (Hill Notation): C₂₃H₃₂O₆
• CAS Number: 50-03-3
• Molecular Weight: 404.50
• EC Number: 200-004-4
• MDL number: MFCD00037714
• Beilstein/REAXYS Number: 2066841
• NACRES: NA.77
• PubChem Substance ID: 24895620
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Properties

• Product Name: Hydrocortisone 21-acetate, ≥98% (HPLC)
• sterility: non-sterile
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• technique(s): permeability assay: suitable
• mp: 223 °C (dec.) (lit.)
• shipped in: ambient
• storage temp.: room temp
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C23H32O6/c1-13(24)29-12-19(27)23(28)9-7-17-16-5-4-14-10-15(25)6-8-21(14,2)20(16)18(26)11-22(17,23)3/h10,16-18,20,26,28H,4-9,11-12H2,1-3H3/t16-,17-,18-,20+,21-,22-,23-/m0/s1
• InChI key: ALEXXDVDDISNDU-JZYPGELDSA-N
• Gene Information: human ... NR3C1(2908), SERPINA6(866)

Description

General description

Hydrocortisone 21-acetate is an adrenocortical steroid. Hydrocortisone acts as an immunosuppressive drug and might suppress systemic inflammatory responses. It is used to treat rheumatoid arthritis and adrenal insufficiency. It also functions as an antiallergic agent.

Safety Information

• pictograms: GHS08
• signalword: Danger
• hcodes: H360Df,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B - STOT RE 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves