The stability of this product in solution after reconstitution has not been specifically determined. However, it is recommended that solutions be stored in working aliquots at −20°C. This practice is considered optimal for maintaining stability, but no exact shelf life duration is provided after reconstitution.
H4001
Hydrocortisone
synthetic (organic), ≥98% (HPLC), anti-inflammatory agent, powder
Hydrocortisone
Synonym(s):
11β,17α,21-Trihydroxypregn-4-ene-3,20-dione, 17-Hydroxycorticosterone, 4-Pregnene-11β,17α,21-triol-3,20-dione, Cortisol, Kendall’s compound F, Reichstein’s substance M
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About This Item
Empirical Formula (Hill Notation):
C21H30O5
CAS Number:
Molecular Weight:
362.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
200-020-1
MDL number:
Beilstein/REAXYS Number:
1354819
Assay:
≥98% (HPLC)
Form:
powder
Pricing and availability is not currently available.
Product Name
Hydrocortisone, ≥98% (HPLC)
biological source
synthetic (organic)
Quality Segment
sterility
non-sterile
assay
≥98% (HPLC)
form
powder
mp
211-214 °C (lit.)
solubility
water: 0.28 g/L at 25 °C
application(s)
cell analysis
shipped in
ambient
storage temp.
room temp
SMILES string
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]4(C)[C@@]2([H])CC[C@]4(O)C(=O)CO
InChI
1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1
InChI key
JYGXADMDTFJGBT-VWUMJDOOSA-N
Gene Information
human ... ABCB1(5243), CYP3A4(1576), NR3C1(2908), SERPINA6(866)
mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126)
rat ... Ar(24208), Nr3c1(24413)
Biochem/physiol Actions
Primary glucocorticoid secreted by the adrenal cortex.
Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.
Features and Benefits
This compound is featured on the Nuclear Receptors (Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
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This Item | |||
|---|---|---|---|
| form powder | form powder | form powder | form liquid |
| assay ≥98% (HPLC) | assay 97.0-102.0% dry basis | assay ≥98% | assay - |
| Quality Level 300 | Quality Level 300 | Quality Level 200 | Quality Level 500 |
| storage temp. room temp | storage temp. - | storage temp. room temp | storage temp. −20°C |
| solubility water: 0.28 g/L at 25 °C | solubility water: soluble 0.28 g/L at 25 °C | solubility chloroform/ethanol (1:1): 50 mg/mL, clear, colorless to very faintly yellow | solubility - |
| shipped in ambient | shipped in - | shipped in ambient | shipped in dry ice |
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signalword
Danger
hcodes
Hazard Classifications
Repr. 1A - STOT RE 2
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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