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930-05A

Human Renal Proximal Tubular Epithelial Cells: HRPTEpC, adult

Synonym(s):

Proximal Tubular Epithelial Cells

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About This Item

NACRES:
NA.81
UNSPSC Code:
41106514
Biological source:
human kidney
Growth mode:
Adherent
Pricing and availability is not currently available.
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biological source

human kidney

Quality Level

packaging

pkg of 500,000 cells

manufacturer/tradename

Cell Applications, Inc

growth mode

Adherent

technique(s)

cell culture | mammalian: suitable

shipped in

dry ice

storage temp.

−196°C

General description

Lot specific orders are not able to be placed through the web. Contact your local sales rep for more details.

Human Renal Proximal Tubular Epithelial Cells (HRPTEpC) provide a useful tool for studying various aspects of pathology and biology of the human renal proximal tubular cells in vitro. HRPTEpC have recently been used in a study of metabolic enzymes responding to energy depletion in renal cells. HRPTEpCs have a pivotal role in kidney function including reabsorbtion of glucose and protein, and also play a part in the glucotoxicity associated with diabetes.

Application

Kidney disease, diabetes, glucotoxicity, pathology. kidney function, reabsorbtion of glucose and protein, biology of renal proximal tubular cells in vitro, metabolic enzymes, cell energy usage.

Biochem/physiol Actions

Kidney

Packaging

First or second passage, >500,000 cells in RenaEpi Basal Medium containing 10% FBS & 10% DMSO.

Analysis Note

Each lot was tested for proper morphology, ability to attach and spread on tissue culture ware surface, and proliferate in RenaEpi Growth Medium, Negative for HIV, Hepatitis B, Hepatitis C, mycoplasma, bacteria, and fungi.

Other Notes

Can be cultured at least 6 population doublings
RenaEpi Basal Medium containing 10% FBS & 10% DMSO

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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This Item
930-05F930-05N230-05F
biological source

human kidney

biological source

human kidney

biological source

human kidney

biological source

human amnion (normal)

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

growth mode

Adherent

growth mode

Adherent

growth mode

Adherent

growth mode

Adherent

Quality Level

100

Quality Level

-

Quality Level

100

Quality Level

100

storage temp.

−196°C

storage temp.

−196°C

storage temp.

−196°C

storage temp.

−196°C

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice


Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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Fatimah K Khalaf et al.
Journal of the American Heart Association, 9(3), e013933-e013933 (2020-02-06)
Background Recent studies have highlighted a critical role for a group of natriuretic hormones, cardiotonic steroid (CTS), in mediating renal inflammation and fibrosis associated with volume expanded settings, such as chronic kidney disease. Immune cell adhesion is a critical step
Duygu Elif Yilmaz et al.
The Journal of biological chemistry, 298(3), 101589-101589 (2022-01-17)
Current immunosuppressive strategies in organ transplantation rely on calcineurin inhibitors cyclosporine A (CsA) or tacrolimus (Tac). Both drugs are nephrotoxic, but CsA has been associated with greater renal damage than Tac. CsA inhibits calcineurin by forming complexes with cyclophilins, whose



Global Trade Item Number

SKUGTIN
930-05A04061833270790

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