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B0770

Brilliant Blue G

≥80% purity (HPLC), powder

Synonym(s):

Acid blue 90, Coomassie Brilliant Blue G

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About This Item

Empirical Formula (Hill Notation):
C47H48N3NaO7S2
CAS Number:
Molecular Weight:
854.02
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
228-058-4
MDL number:
Colour Index Number:
42655
Beilstein/REAXYS Number:
5230822
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Product Name

Brilliant Blue G, pure

Quality Level

assay

≥80.0% (HPLC)

form

powder

technique(s)

microbe id | staining: suitable

color

dark violet

solubility

H2O: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].CCOc1ccc(Nc2ccc(cc2)C(\c3ccc(cc3C)N(CC)Cc4cccc(c4)S([O-])(=O)=O)=C5\C=CC(\C=C5C)=[N+](\CC)Cc6cccc(c6)S([O-])(=O)=O)cc1

InChI

1S/C47H49N3O7S2.Na/c1-6-49(31-35-11-9-13-43(29-35)58(51,52)53)40-21-25-45(33(4)27-40)47(37-15-17-38(18-16-37)48-39-19-23-42(24-20-39)57-8-3)46-26-22-41(28-34(46)5)50(7-2)32-36-12-10-14-44(30-36)59(54,55)56;/h9-30H,6-8,31-32H2,1-5H3,(H2,51,52,53,54,55,56);/q;+1/p-1

InChI key

RWVGQQGBQSJDQV-UHFFFAOYSA-M

Application

Brilliant Blue G has been used for determining the urine protein concentration. It has been used for the protein band detection after SDS-PAGE (sodium dodecyl sulfate polyacrylamide gel electrophoresis). It has been used as a P2X7R (purinergic receptor) antagonist.

Biochem/physiol Actions

P2X7 purinergic receptor antagonist.
Brilliant Blue G is used for staining protein(s) in polyacrylamide gels. It is also a P2X7 purinergic receptor antagonist. The receptor is mainly involved in neuroinflammatory events. In human SOD1G93A amyotrophic lateral sclerosis mouse, administration of brilliant blue G reduces body weight loss. However, it does not affect survival or motor coordination in transgenic mice.

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1 of 1

This Item
B7920B014927816
technique(s)

microbe id | staining: suitable

technique(s)

microbe id | staining: suitable

technique(s)

microbe id | staining: suitable

technique(s)

microbe id | staining: suitable

color

dark violet

color

-

color

-

color

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

solubility

H2O: 1 mg/mL

solubility

H2O: 1 mg/mL

solubility

H2O: 10 mg/mL

solubility

-

form

powder

form

powder

form

powder

form

powder

assay

≥80.0% (HPLC)

assay

≥70% (HPLC)

assay

-

assay

-


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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Neuronal Release of Cytokine IL-3 Triggered by Mechanosensitive Autostimulation of the P2X7 Receptor Is Neuroprotective.
Lim JC, et al.
Frontiers in Cellular Neuroscience, 10, 270-270 (2016)
MATE transport of the E. coli-derived genotoxin colibactin.
Mousa JJ, et al.
Nature microbiology, 1, 15009-15009 (2016)
P2X7 antagonism using Brilliant Blue G reduces body weight loss and prolongs survival in female SOD1G93A amyotrophic lateral sclerosis mice.
PeerJ, e3064-e3064 (2017)



Global Trade Item Number

SKUGTIN
B0770-5G04061835345830
B0770-25G04061835345823
B0770-100G04061835345816

Questions

  1. ブリリアントブルーG(購入した容器のまま)は、室温保管で良いですか?冷所の方が良いですか?

    1 answer
    1. Yes, this product is stored at room temperature in the powder form. However, storing the material in a cool environment will not be detrimental.

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