345802
Gc-Globulin, Mixed Type, Human Plasma
Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.
Synonym(s):
Gc-Globulin, Mixed Type, Human Plasma
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About This Item
Form:
solid
Assay:
≥95% (SDS-PAGE)
Biological source:
human plasma
Pricing and availability is not currently available.
biological source
human plasma
Quality Level
assay
≥95% (SDS-PAGE)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
shipped in
ambient
storage temp.
−20°C
General description
Native Gc-globulin from human plasma. A single polypeptide chain present in plasma at a concentration of about 20-55 mg/100 ml. Functions in the binding and transport of vitamin D. May also play an important role in actin homeostasis; binds monomeric actin with high affinity. Binds membranes of both circulating B and T lymphocytes.
Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.
Application
Gc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.
Physical form
Lyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.
Preparation Note
Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.
Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Di Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
Lee, W.M., et al. 1987. Hepatology7, 825.
Machii, T., et al. 1986. Acta Haematol.75, 26.
Lee, W.M., et al. 1987. Hepatology7, 825.
Machii, T., et al. 1986. Acta Haematol.75, 26.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
1 of 1
This Item | |||
|---|---|---|---|
| biological source human plasma | biological source - | biological source human blood | biological source - |
| assay ≥95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) | assay ≥99% (electrophoresis) | assay >95% (SDS-PAGE) |
| form solid | form solid | form powder | form lyophilized |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| storage condition OK to freeze | storage condition OK to freeze | storage condition - | storage condition OK to freeze |
| shipped in ambient | shipped in ambient | shipped in - | shipped in ambient |
Storage Class
11 - Combustible Solids
wgk
WGK 3
Certificates of Analysis (COA)
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 345802-1MG | 04055977194050 |