1.06265

Sodium acetate trihydrate

extra pure, EMPROVE^® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC, E 262

• Synonym(s): Acetic acid sodium salt trihydrate
• Linear Formula: CH₃COONa · 3H₂O
• CAS Number: 6131-90-4
• Molecular Weight: 136.08
• UNSPSC Code: 12352107
• EC Index Number: 204-823-8
• E Number: E262
• MDL number: MFCD00071557
• Beilstein/REAXYS Number: 3732037

Properties

• Quality Level: 500
• agency: USP, BP, JP, Ph. Eur.
• reg. compliance: FCC
• product line: EMPROVE^® ESSENTIAL
• form: solid
• autoignition temp.: 1112 °F, 607 °C
• pH: 7.5-9 (25 °C, 50 g/L in H₂O)
• pKa: 4.8
• mp: 58 °C
• transition temp: flash point >250 °C (anhydrous substance)
• solubility: 613 g/L
• density: 1.42 g/cm³ at 20 °C
• application(s): liquid formulation; ophthalmics; pharmaceutical; solid formulation
• storage temp.: 15-25°C
• SMILES string: O.O.O.[Na+].CC([O-])=O
• InChI: 1S/C2H4O2.Na.3H2O/c1-2(3)4;;;;/h1H3,(H,3,4);;3*1H2/q;+1;;;/p-1
• InChI key: AYRVGWHSXIMRAB-UHFFFAOYSA-M

Description

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Sodium acetate trihydrate is an acetate buffer system component commonly used in biomolecule downstream chromatography steps as well as in liquid formulation.

Other Notes

Enzyme substrate for acetate kinase (EC 2.7.2.1)

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable