M7633

4-Methylumbelliferyl α-D-galactopyranoside

≥98% (TLC)

• Synonym(s): MU-alpha-GAL
• Empirical Formula (Hill Notation): C₁₆H₁₈O₈
• CAS Number: 38597-12-5
• Molecular Weight: 338.31
• UNSPSC Code: 12352204
• NACRES: NA.32
• PubChem Substance ID: 24897170
• EC Number: 254-031-1
• Beilstein/REAXYS Number: 94674
• MDL number: MFCD00063278

Properties

• Quality Segment: 200
• assay: ≥98% (TLC)
• form: powder
• solubility: water: 50 mg/mL, clear, colorless to very faintly yellow
• fluorescence: λ_ex 317 nm; λ_em 374 nm (pH 9.1), λ_ex 360 nm; λ_em 449 nm (Reaction product)
• storage temp.: −20°C
• SMILES string: CC1=CC(=O)Oc2cc(O[C@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)ccc12
• InChI: 1S/C16H18O8/c1-7-4-12(18)23-10-5-8(2-3-9(7)10)22-16-15(21)14(20)13(19)11(6-17)24-16/h2-5,11,13-17,19-21H,6H2,1H3/t11-,13+,14+,15-,16+/m1/s1
• InChI key: YUDPTGPSBJVHCN-CHUNWDLHSA-N

Description

Application

4-Methylumbelliferyl α-D-galactopyranoside has been used as an artificial substrate to assay α-galactosidase-A activity.[1][2][3]

Biochem/physiol Actions

4-Methylumbelliferyl α-D-galactopyranoside is a fluorogenic substrate for α-galactosidase-A.[4] The enzyme converts the substrate to form a blue fluorescent product, methylumbelliferyl.[3][4] The fluorescence is measured spectrophotometrically.[4]

Preparation Note

4-Methylumbelliferyl α-D-galactopyranoside is soluble in water (50 mg/ml), yielding a clear, colorless to faint yellow solution with the application of heat.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)