This product has not been tested for use as an analytical standard. There are currently three products available that qualify for use as a standard, under the name Ubidecarenone - 2 primary standards and 1 secondary standard. Please see the link below to review these product options:
https://www.sigmaaldrich.com/US/en/substance/ubidecarenone86334303980
C9538
Coenzyme Q10
≥98% (HPLC), powder, antioxidant
Synonym(s):
CoQ10, Q-10, Ubiquinone 50, Ubiquinone-10
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About This Item
Empirical Formula (Hill Notation):
C59H90O4
CAS Number:
Molecular Weight:
863.34
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
EC Number:
206-147-9
MDL number:
Beilstein/REAXYS Number:
1900141
Pricing and availability is not currently available.
Product Name
Coenzyme Q10, ≥98% (HPLC)
Quality Level
assay
≥98% (HPLC)
form
powder
color
yellow to dark orange
mp
49 °C
application(s)
cell analysis
storage temp.
−20°C
SMILES string
O=C(C(OC)=C1OC)C(C/C=C(C)/CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)\C)\C)\C)\C)\C)=C(C)C1=O
InChI
1S/C59H90O4/c1-44(2)24-15-25-45(3)26-16-27-46(4)28-17-29-47(5)30-18-31-48(6)32-19-33-49(7)34-20-35-50(8)36-21-37-51(9)38-22-39-52(10)40-23-41-53(11)42-43-55-54(12)56(60)58(62-13)59(63-14)57(55)61/h24,26,28,30,32,34,36,38,40,42H,15-23,25,27,29,31,33,35,37,39,41,43H2,1-14H3/b45-26+,46-28+,47-30+,48-32+,49-34+,50-36+,51-38+,52-40+,53-42+
InChI key
ACTIUHUUMQJHFO-UPTCCGCDSA-N
General description
Coenzyme Q (CoQ), also known as ubiquinone, is a lipid-soluble antioxidant and is an essential component of the mitochondrial electron transport chain. The molecule contains a biologically active quinone with a benzoquinone ring and an isoprenoid sidechain. Q10 is synthesized in the cytoplasm and mitochondria ([1]) which generates ATP through aerobic cellular respiration. CoQ10 is required for the optimal functioning of the immune system and for cardiovascular health ([2]). The ability to repress inflammatory gene expression exhibits its anti-inflammatory property ([3] ) Genetic failure or ageing results in CoQ10 deficiency, indicated by suppression of immune function. ([1])
Application
Biochem/physiol Actions
Coenzyme Q10 is an endogenous cellular antioxidant and an essential component of the electron transfer chain. CoQ10 takes part in aerobic cellular respiration and generation of energy in the form of ATP.[5]
1 of 1
This Item | |||
|---|---|---|---|
| assay ≥98% (HPLC) | assay ≥97.5% (HPLC) | assay - | assay - |
| form powder | form powder | form liquid | form solid |
| Quality Level 200 | Quality Level 100 | Quality Level 300 | Quality Level - |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| color yellow to dark orange | color faint yellow to dark orange | color - | color - |
| mp 49 °C | mp 49 °C | mp - | mp 49 °C |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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S Ogasahara et al.
Neurology, 35(3), 372-377 (1985-03-01)
In a patient with Kearns-Sayre syndrome, concentration of coenzyme Q10, a component of the mitochondrial electron transport system, was decreased in serum and in the mitochondrial fraction of skeletal muscle. Serum concentrations of lactate and pyruvate were abnormally high, especially
Hassan Ahmadvand et al.
ARYA atherosclerosis, 10(4), 192-198 (2014-09-27)
Diabetes mellitus, one of the leading metabolic syndromes, accounts for highest morbidity and mortality worldwide. In this study, we examined possible protective effect of coenzyme Q10 on lipid profile, atherogenic index, and liver enzyme markers in alloxan-induced type 1 diabetic
Francisco M Gutierrez-Mariscal et al.
Antioxidants (Basel, Switzerland), 10(6) (2021-07-03)
Coenzyme Q10 (CoQ10), which plays a key role in the electron transport chain by providing an adequate, efficient supply of energy, has another relevant function as an antioxidant, acting in mitochondria, other cell compartments, and plasma lipoproteins. CoQ10 deficiency is
Global Trade Item Number
| SKU | GTIN |
|---|---|
| C9538-1G | 04061833530825 |
| C9538-500MG | 04061833530832 |
| C9538-100MG | 04061833530818 |
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Regarding this product, C9538, can it be used as primary reference standard for the content determination of CoQ10?
1 answer-
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