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E0761

Ebelactone A microbial

esterase inhibitor

Synonym(s):

3,11-Dihydroxy-2,4,6,8,10,12-hexamethyl-9-oxo-6-tetradecenoic acid 1,3-lactone

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About This Item

Empirical Formula (Hill Notation):
C20H34O4
CAS Number:
76808-16-7
Molecular Weight:
338.48
NACRES:
NA.77
PubChem Substance ID:
24894373
UNSPSC Code:
12352202
MDL number:
MFCD00036710
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biological source

Streptomyces sp.

Quality Level

100

assay

≥98% (HPLC)

form

powder

solubility

methanol: 10 mg/mL, clear, colorless

storage temp.

2-8°C

SMILES string

[H][C@@]1([C@H](C/C(C)=C/[C@H](C([C@H]([C@@H]([C@@H](CC)C)O)C)=O)C)C)OC([C@H]1C)=O

InChI

1S/C20H34O4/c1-8-12(3)17(21)15(6)18(22)13(4)9-11(2)10-14(5)19-16(7)20(23)24-19/h9,12-17,19,21H,8,10H2,1-7H3/b11-9+/t12-,13-,14+,15+,16+,17-,19+/m1/s1

InChI key

WOISDAHQBUYEAF-QIQXJRRPSA-N

General description

Esterase inhibitors produced by Streptomyces sp. MG7-G1 strain

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This Item
B6542B5936N7779
Ebelactone A microbial esterase inhibitor

Sigma-Aldrich

E0761

Ebelactone A microbial

Brefeldin A ≥99% (HPLC and TLC), BioXtra, Molecular Biology

Sigma-Aldrich

B6542

Brefeldin A

Brefeldin A Ready Made Solution, from Penicillium brefeldianum, 10 mg/mL in DMSO

Sigma-Aldrich

B5936

Brefeldin A

Nojirimycin bisulfite microbial solid

Sigma-Aldrich

N7779

Nojirimycin bisulfite microbial

assay

≥98% (HPLC)

assay

≥99% (HPLC and TLC)

assay

-

assay

≥98% (TLC)

biological source

Streptomyces sp.

biological source

Penicillium brefeldianum

biological source

Penicillium brefeldianum

biological source

Streptomyces sp.

Quality Level

100

Quality Level

300

Quality Level

200

Quality Level

100

form

powder

form

powder

form

ready-to-use solution

form

solid

solubility

methanol: 10 mg/mL, clear, colorless

solubility

DMSO: 10 mg/mL (Store stock solutions at -20 °C)

solubility

DMSO: 10 mg/mL

solubility

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX7876
MKCP5578
MKCL2829
MKCJ1250
MKCH0498

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I A Hoskins et al.
American journal of obstetrics and gynecology, 163(6 Pt 1), 1944-1947 (1990-12-01)
Assessment of leukocyte esterase activity in amniotic fluid for the rapid and reliable diagnosis of chorioamnionitis has been demonstrated previously. We compared in vitro inhibition of esterase activity in amniotic fluid with bacterial cultures to identify the origins of the
Gianfranco De Pascale et al.
The Journal of antibiotics, 64(7), 483-487 (2011-04-28)
Homoserine transacetylase (HTA) catalyzes the transfer of an acetyl group from acetyl-CoA to the hydroxyl group of homoserine. This is the first committed step in the biosynthesis of methionine (Met) from aspartic acid in many fungi, Gram-positive and some Gram-negative
A Scaloni et al.
The Journal of biological chemistry, 269(21), 15076-15084 (1994-05-27)
The presence of a cysteine residue(s) near the active site of acylpeptide hydrolase was suggested by inactivation of the enzyme with sulfhydryl-modifying agents and by the substantial protection against inactivation afforded by the competitive inhibitor acetylmethionine. 5,5'-dithiobis-(2-nitrobenzoate) titrations of the
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Global Trade Item Number

SKUGTIN
E0761-1MG04061833601228

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