1285750

Flurbiprofen

United States Pharmacopeia (USP) Reference Standard

• Szinonimák: (±)-2-Fluoro-α-methyl-4-biphenylacetic acid, L-790,330
• Lineáris képlet: C₆H₅C₆H₃(F)CH(CH₃)CO₂H
• CAS-szám: 5104-49-4
• Molekulatömeg: 244.26
• MDL-szám: MFCD00079303
• UNSPSC kód: 41116107
• PubChem Substance ID: 329749901
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: flurbiprofen
• gyártó/kereskedő neve: USP
• mp: 110-112 °C (lit.)
• alkalmazás(ok): pharmaceutical (small molecule)
• format: neat
• SMILES string: CC(C(O)=O)c1ccc(c(F)c1)-c2ccccc2
• InChI: 1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
• Nemzetközi kémiai azonosító kulcs: SYTBZMRGLBWNTM-UHFFFAOYSA-N
• Géninformáció: human ... PTGS1(5742) , PTGS2(5743)

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Flurbiprofen USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Flurbiprofen Tablets
• Flurbiprofen Sodium
• Flurbiprofen Sodium Ophthalmic Solution

Biokémiai/fiziológiai hatások

Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.

Analízis megjegyzés

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Egyéb megjegyzések

Sales restrictions may apply.

Biztonsági adatok

• Piktogramok: GHS06
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H301
• Óvintézkedésre vonatkozó mondatok: P264 - P270 - P301 + P310 - P405 - P501
• Veszélyességi osztályok: Acute Tox. 3 Oral
• Tárolási osztály kódja: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable