F0285200

Flurbiprofen

European Pharmacopoeia (EP) Reference Standard

• Szinonimák: (±)-2-Fluoro-α-methyl-4-biphenylacetic acid, L-790,330
• Lineáris képlet: C₆H₅C₆H₃(F)CH(CH₃)CO₂H
• CAS-szám: 5104-49-4
• Molekulatömeg: 244.26
• MDL-szám: MFCD00079303
• UNSPSC kód: 41116107
• PubChem Substance ID: 329799649
• NACRES: NA.24

Tulajdonságok

• grade: pharmaceutical primary standard
• API-család: flurbiprofen
• gyártó/kereskedő neve: EDQM
• mp: 110-112 °C (lit.)
• alkalmazás(ok): pharmaceutical (small molecule)
• Formátum: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: CC(C(O)=O)c1ccc(c(F)c1)-c2ccccc2
• InChI: 1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
• Nemzetközi kémiai azonosító kulcs: SYTBZMRGLBWNTM-UHFFFAOYSA-N
• Géninformáció: human ... PTGS1(5742) , PTGS2(5743)

Leírás

Általános leírás

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Alkalmazás

Flurbiprofen EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biokémiai/fiziológiai hatások

Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity.

Kiszerelés

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Egyéb megjegyzések

Sales restrictions may apply.

Biztonsági adatok

• Piktogramok: GHS06
• Figyelmeztetés: Danger
• Figyelmeztető mondatok: H301
• Óvintézkedésre vonatkozó mondatok: P301 + P310 + P330
• Veszélyességi osztályok: Acute Tox. 3 Oral
• Tárolási osztály kódja: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable