569232-U

Discovery^® C18 (5 µm) HPLC Columns

L × I.D. 12.5 cm × 4.6 mm, HPLC Column

• Szinonimák: Discovery RP18 HPLC Column
• UNSPSC kód: 41115700
• eCl@ss: 32110501
• NACRES: SB.52

Tulajdonságok

• Terméknév: Discovery^® C18 HPLC Column, 5 μm particle size, L × I.D. 12.5 cm × 4.6 mm
• Anyagok: stainless steel column
• Minőségi szint: 100
• Ügynökség: suitable for USP L1
• termékcsalád: Discovery^®
• Jellemzők: endcapped
• gyártó/kereskedő neve: Discovery^®
• kiszerelés: 1 ea of
• a címkézés mértéke: 12% Carbon loading
• Paraméterek: ≤70 °C temp. range; 400 bar pressure (5801 psi)
• technika/technikák: HPLC: suitable; LC/MS: suitable
• H × belső átmérő: 12.5 cm × 4.6 mm
• külső felület: 300 m²/g
• felület bevonatolás: 3 μmol/m²
• szennyeződések: <10 ppm metals
• Mátrix: silica gel, high purity, spherical particle platform; fully porous particle
• mátrix aktív csoport: C18 (octadecyl) phase
• részecskeméret: 5 μm
• pórusméret: 180 Å
• Üzemi pH tartomány: 2-8
• alkalmazás(ok): food and beverages
• elválasztástechnika: reversed phase

Leírás

Általános leírás

Use Discovery® C18 for any method that specifies a C18. The exceptional peak shape, reproducibility, and stability make it the column of choice for all C18 methods from demanding to routine.

Alkalmazás

• Rat Pharmacokinetics and In Vitro Metabolite Identification of KM-819, a Parkinson′s Disease Candidate, Using LC-MS/MS and LC-HRMS.: This study underscores the utility of theDiscovery^® C18 HPLC Column in pharmacokinetic profiling and metabolite identification of a novel therapeutic agent, demonstrating its critical role in the development of Parkinson′s disease treatments (Choi et al., 2024).


• Determination of 2,4-dimethylhydroxybenzene by chromatographic methods in forensic toxicological research of biological material.: Highlights the application of the Discovery^® C18 HPLC Column in forensic toxicology, enhancing the detection and quantification of toxic substances within biological samples, vital for legal and medical investigations (Chernova et al., 2024).


• High-throughput microfluidic chip with silica gel-C18 channels for cyclotide separation.: Illustrates the integration of the Discovery^® C18 HPLC Column in a microfluidic setting for efficient and high-throughput separation of cyclotides, offering advancements in peptide and protein analysis (Ebrahimi et al., 2023).


• Priestia megaterium Metabolism: Isolation, Identification of Naringenin Analogues and Genes Elevated Associated with Nanoparticle Intervention.: This research utilizes the Discovery^® C18 HPLC Column for the advanced study of microbial metabolism under nanoparticle intervention, pushing the boundaries of biotechnological and pharmaceutical research (Al-Theyab et al., 2023).


• A practical strategy enabling more reliable identification of ginsenosides from Panax quinquefolius flower by dimension-enhanced liquid chromatography/mass spectrometry and quantitative structure-retention relationship-based retention behavior prediction.: Demonstrates the versatility of the Discovery^® C18 HPLC Column in complex botanical analyses, particularly in enhancing the reliability of ginsenoside identification, crucial for the development of herbal medicinal products (Sun et al., 2023).

Tulajdonságok és előnyök

• Excellent reproducibility
• Exceptional peak shape for basic and acidic analytes
• Stable, low-bleed LC-MS separations
• Separation of peptides and small proteins
• Lower hydrophobicity than many comparable C18 columns, providing faster analysis

Javasolt termékek

Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Jogi információk

Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany