Összes fotó(1)
Fontos dokumentumok
SBR00032
MIT HCl Ready Made Solution
95 mg/mL in water (9.5%)
Szinonimák:
2-Methyl-1,2-thiazol-3-one, Methylisothiazolinone HCl, Methylisothiazolinone hydrochloride
Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez
Összes fotó(1)
About This Item
UNSPSC kód:
51102829
NACRES:
NA.76
Javasolt termékek
form
liquid
Minőségi szint
koncentráció
95 mg/mL in water (9.5%)
antibiotikus hatásspektrum
Gram-negative bacteria
Gram-positive bacteria
Hatásmechanizmus
protein synthesis | interferes
tárolási hőmérséklet
2-8°C
InChI
1S/C4H5NOS.ClH/c1-5-4(6)2-3-7-5;/h2-3H,1H3;1H
Nemzetközi kémiai azonosító kulcs
SJXPQSRCFCPWQQ-UHFFFAOYSA-N
Looking for similar products? Látogasson el ide Útmutató a termékösszehasonlításhoz
Általános leírás
Methylisothiazolinone, also known as 2-Methyl-4-isothiazolin-3-one, is a potent synthetic biocide and preservative belonging to the group of isothiazolinones. It effectively controls microbial growth and acts as a broad-spectrum antibiotic, similar to the function and performance of bromonitrodioxane. It is effective against both gram-positive and gram-negative bacteria, as well as yeast and fungi. Additionally, it serves as an antifouling biocide, an antimicrobial agent, and an antifungal agent. 2-Methyl-4-isothiazolin-3-one is utilized in microbiology and cell biology applications to effectively prevent the growth of bacterial contaminants, ensuring the purity of cell lines.
Alkalmazás
Methylisothiazolinone (MIT) has been used:
- in research on the effects of the N-methyl D-aspartate (NMDA) receptor antagonist kynurenic acid on human cortical development [1]
- as a cytotoxic substance to investigate its effect on bronchial epithelial cells (BEAS-2B cells) and role in apoptotic cell death(2)
- to research the effects of tyrosine phosphorylation on focal adhesion kinase (FAK) activity in the development of neural axons and dendrites(3)
Biokémiai/fiziológiai hatások
Mode of Action: Inhibits the growth of microorganisms by disrupting the normal function of microbial cells and interferes with essential cellular processes.
Activity Spectrum: Active against Gram-positive and Gram-negative bacteria, as well as fungi, when used in combination with methylchloroisothiazolinone (MCI)
Activity Spectrum: Active against Gram-positive and Gram-negative bacteria, as well as fungi, when used in combination with methylchloroisothiazolinone (MCI)
Tulajdonságok és előnyök
- Ready available solution reduce the need for preparation time
- Commonly used in Cell Biology and Biochemical applications
- High quality antibiotic suitable for mulitple research applications
Egyéb megjegyzések
For additional information on our range of Biochemicals, please complete this form.
kapcsolódó termék
Product No.
Leírás
Árazás
Figyelmeztetés
Danger
Figyelmeztető mondatok
Óvintézkedésre vonatkozó mondatok
Veszélyességi osztályok
Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1
Egyéb veszélyek
Tárolási osztály kódja
8B - Non-combustible corrosive hazardous materials
WGK
WGK 3
Lobbanási pont (F)
Not applicable
Lobbanási pont (C)
Not applicable
Analitikai tanúsítványok (COA)
Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.
Már rendelkezik ezzel a termékkel?
Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.
Shen Du et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 22(17), 7408-7416 (2002-08-28)
Neurodegenerative disorders in humans may be triggered or exacerbated by exposure to occupational or environmental agents. Here, we show that a brief exposure to methylisothiazolinone, a widely used industrial and household biocide, is highly toxic to cultured neurons but not
Zhengxi Wei et al.
Toxicology letters, 338, 67-77 (2020-12-09)
Chemical-peptide conjugation is the molecular initiating event in skin sensitization. The OECD test guideline uses a high-performance liquid chromatography/ultraviolet (HPLC/UV) detection method to quantify chemical-peptide conjugation in a direct peptide reactivity assay (DPRA), which measures the depletion of two synthetic
Erol Capkin et al.
Chemosphere, 182, 720-729 (2017-05-23)
Triclosan (TRC), chloroxylenol (PCMX) and methylisothiazolinone (MIT) have been commonly used as an antimicrobial in soaps while borax (BRX) is used in household cleaning. After using these chemicals, they are washed down drains and getting into the aquatic ecosystem in
Eun-Jung Park et al.
Toxicology in vitro : an international journal published in association with BIBRA, 62, 104661-104661 (2019-10-21)
Methylisothiazolinone (MIT) has been used in wide spectrum of fields due to its ability to inhibit microbial proliferation with low toxicity. Meanwhile, in Korea, the concern about the hazardous effects of MIT was amplified by the occurrence of patients that
Mari Paz Castanedo-Tardana et al.
Dermatitis : contact, atopic, occupational, drug, 24(1), 2-6 (2013-01-24)
The preservative methylisothiazolinone (MI) is the American Contact Dermatitis Society Contact Allergen of the Year for 2013. Because the use of MI in cosmetics and toiletries in the United States rises, MI exposure also rises. Although it might seem likely
Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.
Lépjen kapcsolatba a szaktanácsadással