Ugrás a tartalomra
Merck

N8160

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide phosphate sodium salt

pkg of 10 mg (per vial)

Szinonimák:

β-NADP-Na, β-NADP-sodium salt, Coenzyme II sodium salt, NADP, TPN, TPN-Na, Triphosphopyridine nucleotide sodium salt

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Lineáris képlet:
C21H27N7O17P3 · Na
CAS-szám:
Molekulatömeg:
765.39
Beilstein:
4779954
EC-szám:
MDL-szám:
UNSPSC kód:
41106305
PubChem Substance ID:
NACRES:
NA.51

form

powder

Minőségi szint

kiszerelés

pkg of 10 mg (per vial)

mp

175-178 °C (dec.) (lit.)

oldhatóság

water: 0.05 g/L

tárolási hőmérséklet

−20°C

SMILES string

[Na+].[H]O[H].NC(=O)c1ccc[n+](c1)C2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@@H]([C@@H]3O)P(O)(O)=O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O

InChI

1S/C21H28N7O16P3.Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(45(33,34)35)14(30)11(43-21)6-41-47(38,39)44-46(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;/h1-4,7-8,10-11,13-16,20-21,29-31H,5-6H2,(H7-,22,23,24,25,32,33,34,35,36,37,38,39);;1H2/q;+1;/p-1/t10-,11-,13-,14-,15-,16-,20?,21-;;/m1../s1

Nemzetközi kémiai azonosító kulcs

NLIGHACCLYZCOM-FHQWUTKFSA-M

Looking for similar products? Látogasson el ide Útmutató a termékösszehasonlításhoz

Alkalmazás

β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Biokémiai/fiziológiai hatások

Electron acceptor

Egyéb megjegyzések

Packaged based on NADP content as determined by UV-Vis.
This is the common form of NADP. Do not confuse with 3′-NADP or α-NADP.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves, type N95 (US)


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Haiqin Chen et al.
Scientific reports, 5, 11247-11247 (2015-06-11)
Microorganisms are valuable resources for lipid production. What makes one microbe but not the other able to efficiently synthesize and accumulate lipids is poorly understood. In the present study, global gene expression prior to and after the onset of lipogenesis
Rong Zhang et al.
American journal of respiratory and critical care medicine, 192(3), 315-323 (2015-05-07)
Lung-protective ventilatory strategies have been widely used in patients with acute respiratory distress syndrome (ARDS), but the ARDS mortality rate remains unacceptably high and there is no proven pharmacologic therapy. Mechanical ventilation can induce oxidative stress and lung fibrosis, which
Bevan P Gang et al.
Cancer biology & therapy, 15(11), 1533-1541 (2014-12-09)
Deregulated metabolism is gaining recognition as a hallmark of cancer cells, and is being explored for therapeutic potential. The Warburg effect is a metabolic phenotype that occurs in 90% of tumors, where glycolysis is favored despite the presence of oxygen.
María Apellániz-Ruiz et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 21(2), 322-328 (2014-11-16)
Paclitaxel, a widely used chemotherapeutic drug, can cause peripheral neuropathies leading to dose reductions and treatment suspensions and decreasing the quality of life of patients. It has been suggested that genetic variants altering paclitaxel pharmacokinetics increase neuropathy risk, but the
Dandan Liang et al.
Journal of molecular and cellular cardiology, 82, 63-74 (2015-03-12)
Diabetes mellitus is strongly associated with cardiomyopathy. The underlying mechanisms for the development of diabetic cardiomyopathy are complex and not completely understood. Recent studies showed that epidermal growth factor receptors (EGFRs) are involved in diabetes-induced cardiac injury. However, the role

Tudóscsoportunk valamennyi kutatási területen rendelkezik tapasztalattal, beleértve az élettudományt, az anyagtudományt, a kémiai szintézist, a kromatográfiát, az analitikát és még sok más területet.

Lépjen kapcsolatba a szaktanácsadással