L8912

L-Leucine

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, JP, USP testing specifications

• Szinonimák: (S)-Leucine, (S)-2-Amino-4-methylpentanoic acid
• Lineáris képlet: (CH₃)₂CHCH₂CH(NH₂)CO₂H
• CAS-szám: 61-90-5
• Molekulatömeg: 131.17
• Beilstein: 1721722
• EC-szám: 200-522-0
• MDL-szám: MFCD00002617
• UNSPSC kód: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 24896510
• NACRES: NA.26

Tulajdonságok

• Terméknév: L-Leucine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%
• biológiai forrás: non-animal source
• Minőségi szint: 300
• Ügynökség: USP/NF; meets EP testing specifications; meets JP testing specifications; meets USP testing specifications
• Teszt: 98.5-101.0%
• Forma: powder
• optikai aktivitás: [α]20/D 14.9 to 16.0°, c = 4 in 6 M HCl; [α]25/D 14.9 to 17.3 °, c = 4 in 6 M HCl
• minőség: meets EP, JP, USP testing specifications
• technika/technikák: cell culture | mammalian: suitable
• szennyeződések: endotoxin, tested
• szín: white
• mp: >300 °C (lit.)
• oldhatóság: 1 M HCl: 50 mg/mL
• kation nyomok: As: ≤1 ppm; Fe: ≤10 ppm; NH₄⁺: <0.02%; heavy metals: ≤10 ppm
• alkalmazás(ok): peptide synthesis; pharmaceutical (small molecule)
• funkcionális csoport: amine; carboxylic acid
• tárolási hőmérséklet: room temp
• SMILES string: CC(C)C[C@H](N)C(O)=O
• InChI: 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1
• Nemzetközi kémiai azonosító kulcs: ROHFNLRQFUQHCH-YFKPBYRVSA-N

Leírás

Általános leírás

Leucine is a non-glucogenic, and essential amino acid. It is a branched-chain amino acid that is a structural component of proteins.

Alkalmazás

L-Leucine has been used:

• as a hypertrophic agent to monitor its effects on myotubes.
• as a component of PMG media for culturing yeast.
• in myotube protein synthesis analysis in skeletal muscle cells.
• to study its effects on hepatic lipid metabolism.

Biokémiai/fiziológiai hatások

Leucine plays a role in intracellular signaling, gene transcription, and translation. It promotes the synthesis of protein by activating the mammalian target of the rapamycin (mTOR) signaling pathway in placental cells, skeletal muscles, and adipose tissue. Leucine inhibits protein degradation and promotes mitochondrial biogenesis, glucose metabolism, and fatty acid oxidation to provide energy for protein synthesis.

Egyéb megjegyzések

For additional information on our range of Biochemicals, please complete this form.

The product is intended for laboratory use only, and it is not suitable for drug, household, or other purposes.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)