K3125

Kojic acid

≥98.5% (HPLC), powder, tyrosinase inhibitor

• Szinonimák: 2-Hydroxymethyl-5-hydroxy-γ-pyrone, 5-Hydroxy-2-hydroxymethyl-4H-4-pyranone
• Tapasztalati képlet (Hill-képlet): C₆H₆O₄
• CAS-szám: 501-30-4
• Molekulatömeg: 142.11
• Beilstein: 120895
• EC-szám: 207-922-4
• MDL-szám: MFCD00006580
• UNSPSC kód: 12352106
• PubChem Substance ID: 24896226
• NACRES: NA.77

Tulajdonságok

• product name: Kojic acid,
• Teszt: ≥98.5% (HPLC)
• Minőségi szint: 200
• form: powder
• mp: 152-155 °C (lit.)
• SMILES string: OCC1=CC(=O)C(O)=CO1
• InChI: 1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2
• Nemzetközi kémiai azonosító kulcs: BEJNERDRQOWKJM-UHFFFAOYSA-N

Leírás

Alkalmazás

Kojic acid has been used:

• as an inhibitor of tyrosinase in guinea pigs pigmented hyperopic (PH)
• as a reference inhibitor standard for screening tyrosinase inhibition
• as a positive control for inhibition of tyrosinase in B16F10 melanoma cells

Biokémiai/fiziológiai hatások

Kojic acid is derived from some fungal species such as, Aspergillus, Acetobacter and Penicillium.. It halts melanin synthesis by inhibiting tyrosinase enzyme. It is used in the preparation of skin whitening cosmetics. However, kojic acid usage is minimal in cosmetics, as it induces skin irritation by its unstability and cytotoxic nature during long storage. It is an antioxidant and elicits radioprotective effects on chelating with manganese and zinc.

Tyrosinase inhibitor.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)