Ugrás a tartalomra
Merck

I9140

Sigma-Aldrich

IgG from goat serum

technical grade, ≥80% (SDS-PAGE), buffered aqueous solution

Szinonimák:

Goat IgG

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

MDL-szám:
UNSPSC kód:
12352203
NACRES:
NA.46

konjugátum

unconjugated

Minőségi szint

grade

technical grade

Teszt

≥80% (SDS-PAGE)

form

buffered aqueous solution

technika/technikák

ChIP: suitable
immunohistochemistry: suitable

kiszállítva

dry ice

tárolási hőmérséklet

−20°C

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Általános leírás

Goat IgG is a glycoprotein antibody that is fractionated from pooled normal goat serum. In immunoelectrophoresis, goat IgG yields a single major arc of precipitation in the γ region against anti-goat IgG and anti-goat whole serum. Minor γ arcs may also be observed against anti-goat whole serum.
IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections
Goat IgG is purified from normal goat serum by fractionation.

Alkalmazás

In immunohistochemical applications, IgG from goat serum can be used as a blocking agent (500 μg/ml in paraformaldehyde-fixed mouse uterus sections) or as a negative control (1:56000 in pig cecal tissue).
Technical grade IgG may be used as an economical alternative to the reagent grade immunoglobulins, in applications where high purity is not required. Goat IgG was used as negative control antibody in immunohistochemical staining of cecal tissue of pigs at a dilution of 1:56000. Goat IgG was used in immunohistochemistry of rat brain sections at a concentration of 2 μg/ml. The antibody was also used in chromatin immunoprecipitation and as control in infection inhibition assay.

Fizikai forma

Solution in 0.01 M phosphate buffered saline, pH 7.2 containing 15 mM sodium azide

Jogi nyilatkozat

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Tárolási osztály kódja

10 - Combustible liquids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Malene M Nørgaard et al.
The Southeast Asian journal of tropical medicine and public health, 36(6), 1394-1398 (2006-04-14)
The pig has been proposed as a model for human schistosomiasis japonica and the use of this animal model is increasing. The inflammatory response to schistosome infection in the liver and intestine of the pig shows morphological differences, and only
Kanin Salao et al.
Biology open, 5(5), 620-630 (2016-04-27)
Intracellular chloride channel protein 1 (CLIC1) participates in inflammatory processes by regulating macrophage phagosomal functions such as pH and proteolysis. Here, we sought to determine if CLIC1 can regulate adaptive immunity by actions on dendritic cells (DCs), the key professional
Michio Kitajima et al.
Archives of histology and cytology, 67(5), 465-474 (2005-03-23)
The arylhydrocarbon receptor (AhR) is a nuclear transcription factor mediating toxic effects of chemicals such as dioxins. The 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a member of polyhalogenated aromatic hydrocarbons family, exerts a wide-variety of toxic effects in a tissue- and species-specific manner including
Kanin Salao et al.
Parasite immunology, 41(1), e12603-e12603 (2018-11-19)
Liver fluke infection caused by Opisthorchis viverrini induces several hepatobiliary conditions including advanced periductal fibrosis (APF) and cholangiocarcinoma (CCA), but >25% of the infected population develops APF and 1% develop CCA. The innate immune response is the first line of
Gillian E Stillfried et al.
Breast cancer research : BCR, 9(1), R14-R14 (2007-01-30)
The regulation of extracellular proteolytic activity via the plasminogen activation system is complex, involving numerous activators, inhibitors, and receptors. Previous studies on monocytic and colon cell lines suggest that plasmin pre-treatment can increase plasminogen binding, allowing the active enzyme to

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