G6752

Guanosine

≥98%

• Szinonimák: 9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside
• Tapasztalati képlet (Hill-képlet): C₁₀H₁₃N₅O₅
• CAS-szám: 118-00-3
• Molekulatömeg: 283.24
• Beilstein: 625911
• EC-szám: 204-227-8
• MDL-szám: MFCD00010182
• UNSPSC kód: 41106305
• PubChem Substance ID: 24895268
• NACRES: NA.51

Tulajdonságok

• biológiai forrás: microbial
• Minőségi szint: 100; 200
• Teszt: ≥98%
• Forma: powder
• mp: 250 °C (dec.) (lit.)
• oldhatóság: formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
• SMILES string: [H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1
• InChI: 1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
• Nemzetközi kémiai azonosító kulcs: NYHBQMYGNKIUIF-UUOKFMHZSA-N

Leírás

Általános leírás

Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid, intestinal cells, blood-brain barrier and in brain microvessels.

Alkalmazás

Guanosine has been used:

• as a reference standard for the analysis of glucosinolates by high-performance liquid chromatography with diode-array detection and electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MS)
• as a component of Mouse Embryonic Fibroblasts (MEFs) culture
• as a standard for the detection of residual RNA contaminant in oil palm plant genome samples by HPLC

Biokémiai/fiziológiai hatások

Guanosine nucleoside elicits cellular effect as the guanine-based purinergic system. It modulates glutamate uptake by glutamate transporters. It may have neuroprotective functionality in central nervous system disorders. Guanosine promotes neurite arborization, outgrowth, proliferation and differentiation. Administration of guanosine replenished GTP and elicits protective function in renal ischemic injury.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 2
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges