Ugrás a tartalomra
Merck

A8763

Sigma-Aldrich

Albumin from human serum

lyophilized powder, essentially globulin free, ≥99% (agarose gel electrophoresis)

Szinonimák:

HSA

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

CAS-szám:
EC-szám:
MDL-szám:
UNSPSC kód:
12352202
eCl@ss:
42010201
NACRES:
NA.25

biológiai forrás

human

Minőségi szint

Teszt

≥99% (agarose gel electrophoresis)

Forma

lyophilized powder

molekulatömeg

monomer calculated mol wt 66478 Da

technika/technikák

ELISA: suitable
tissue culture: suitable
western blot: suitable

szennyeződések

HIV I and HIVII, HCV and HBsAg, tested negative

oldhatóság

H2O: soluble 20 mg/mL

UniProt elérési szám

tárolási hőmérséklet

2-8°C

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

Nemzetközi kémiai azonosító kulcs

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Géninformáció

human ... ALB(213)

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Általános leírás

Albumin is the most copious protein in blood plasma. Liver produces human albumin.

Alkalmazás

Albumin was used to test its effect on the in vitro bactericidal activity of cefditoren against penicillin-resistant Streptococcus pneumonia. It has been clinically used in serious and often life-threatening conditions, such as shock and blood loss due to trauma, burns, and surgery.
Albumin was used to study albumin-induced apoptosis in proximal tubule cells. It was also used in cell adhesion molecules and surface treatment studies.

Biokémiai/fiziológiai hatások

Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin can also bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influences their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has varied effects on its physiological function.
Serum albumin functions as a carrier protein for steroids, fatty acids, and thyroid hormones, and is vital in regulating the colloidal osmotic pressures of blood. Albumin is also seen to bind to exogenous substances, particularly drugs (e.g., ibuprofen, warfarin), and strongly influence their pharmacokinetics. Oxidative stress leading to changes in the redox state of albumin has widely varied effects on its physiological function.

Egyéb megjegyzések

View more information on human serum albumin.

Jogi nyilatkozat

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable

Egyéni védőeszköz

Eyeshields, Gloves


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Analitikai tanúsítványok (COA)

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Dokumentumtár megtekintése

Tamás Pivarcsik et al.
Pharmaceuticals (Basel, Switzerland), 14(6) (2021-06-03)
In this work, the various biological activities of eight organoruthenium(II) complexes were evaluated to reveal correlations with their stability and reactivity in aqueous media. Complexes with general formula [Ru(η6-p-cymene)(X,Y)(Z)] were prepared, where (X,Y) represents either an O,O-ligand (β-diketone), N,O-ligand (8-hydroxyquinoline)
H K Parmentier et al.
Poultry science, 88(3), 536-542 (2009-02-13)
To mimic airborne immune challenges, layer hens were intratracheally and concurrently challenged with various doses of the protein antigen human serum albumin (HuSA) and the pathogen-associated molecular pattern lipopolysaccharide (LPS) at 7 and 13 wk of age. All groups received
Mateusz P Czub et al.
Molecular pharmacology, 98(6), 648-657 (2020-09-27)
Protein tyrosine phosphatase (PTP) 4A3 is frequently overexpressed in human solid tumors and hematologic malignancies and is associated with tumor cell invasion, metastasis, and a poor patient prognosis. Several potent, selective, and allosteric small molecule inhibitors of PTP4A3 were recently
Nóra V May et al.
Molecules (Basel, Switzerland), 26(9) (2021-06-03)
Copper(II) complexes of thiosemicarbazones (TSCs) often exhibit anticancer properties, and their pharmacokinetic behavior can be affected by their interaction with blood transport proteins. Interaction of copper(II) complexes of an {N,N,S} donor α-N-pyridyl TSC (Triapine) and an {O,N,S} donor 2-hydroxybenzaldehyde TSC
Zonghua Liu et al.
Biomaterials, 31(12), 3364-3373 (2010-02-04)
Hydrophobically derivatized hyperbranched polyglycerol (HPG)-polyethylene glycol (PEG) polymers bearing stearoyl chains (HPG-C18-PEG) were originally developed as human serum albumin substitutes and further as a unimolecular drug delivery system. In view of these in vivo applications and the potential for membrane

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