Ugrás a tartalomra
Merck
Összes fotó(1)

Fontos dokumentumok

126654

Sigma-Aldrich

Albumin, Human Serum, Non-denatured

Szinonimák:

Albumin, Human Serum, Non-denatured

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

CAS-szám:
MDL-szám:
UNSPSC kód:
12352202
NACRES:
NA.25

Teszt

≥95% (SDS-PAGE)

Forma

lyophilized solid (Salt-free)

gyártó/kereskedő neve

Calbiochem®

tárolási körülmény

OK to freeze

pI 

4.7

oldhatóság

water: 20 mg/mL

kiszállítva

ambient

tárolási hőmérséklet

2-8°C

SMILES string

FC(F)(F)C(F)(F)C(F)(F)F

InChI

1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11

Nemzetközi kémiai azonosító kulcs

QYSGYZVSCZSLHT-UHFFFAOYSA-N

Általános leírás

High purity plasma protein prepared under non-denaturing conditions.
Human serum albumin (HSA) is the most abundant protein present in the plasma. It is a monomeric multi-domain macromolecule comprising three homologous domains, numbered I, II, and III. Each domain consists of subdomains A and B with common structural motifs. The HSA gene is mapped to the human chromosome 4q13.3.

Alkalmazás

Albumin, human serum, non-denatured has been used:
  • to determine the contribution of albumin protein complexes to esterase activity in saliva,
  • in tris buffer for monomer degradation studies and in protein adhesion assay
  • to study the effect of Cu2+ and Zn2+ ions on human serum albumin interaction with plasma unsaturated fatty acids

Biokémiai/fiziológiai hatások

Human serum albumin (HSA) functions as a carrier for fatty acids, steroids, and thyroid hormones. It is used as a supplement in cell culture medium to produce vaccines and pharmaceuticals. HSA is a potential biomarker for various diseases, like cancer, rheumatoid arthritis, ischemia, and post-menopausal obesity. It is also used to treat surgical blood loss, trauma, hemorrhage, and cardiopulmonary bypass. HSA is implicated in biological applications such as implantable biomaterials, surgical adhesives and sealants, and bio chromatography.

Figyelmeztetés

Toxicity: Standard Handling (A)

Elkészítési megjegyzés

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Feloldás

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Egyéb megjegyzések

Travis, J., and Pannell, R. 1973. Clin. Chem. Acta49, 49.

Jogi információk

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Jogi nyilatkozat

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Tárolási osztály kódja

11 - Combustible Solids

WGK

WGK 3

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

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Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Ekaterina A Litus et al.
International journal of molecular sciences, 23(11) (2022-06-11)
The deposition of amyloid-β peptide (Aβ) in the brain is a critical event in the progression of Alzheimer's disease (AD). This Aβ deposition could be prevented by directed enhancement of Aβ binding to its natural depot, human serum albumin (HSA).
Yasaman Delaviz et al.
Polymers, 9(8) (2017-08-17)
The monomeric components of resin composites in dental restorative materials are susceptible to hydrolysis in the oral cavity. The main objective of this study was to assess the bio-stability of fluorinated urethane dimethacrylates and determine the nature of fluoro-chemistry interactions
Kuihua Cai et al.
Dental materials : official publication of the Academy of Dental Materials, 30(8), 848-860 (2014-06-22)
The ester linkages contained within dental resin monomers (such as Bisphenol A-glycidylmethacrylate (BisGMA) and triethylene glycol dimethacrylate (TEGDMA)) are susceptible to hydrolytic degradation by salivary esterases, however very little is known about the specific esterase activities implicated in this process.
Minhtri K Nguyen et al.
American journal of physiology. Renal physiology, 292(5), F1652-F1656 (2007-02-15)
Pseudohyponatremia is a clinical condition characterized by an increased fraction of protein or lipid in plasma, thereby resulting in an artificially low plasma sodium concentration ([Na(+)](p)). Since the automated method of measuring [Na(+)](p) in most laboratories involves the use of
Onofrio Zirafi et al.
Cell reports, 11(5), 737-747 (2015-04-30)
CXCL12-CXCR4 signaling controls multiple physiological processes and its dysregulation is associated with cancers and inflammatory diseases. To discover as-yet-unknown endogenous ligands of CXCR4, we screened a blood-derived peptide library for inhibitors of CXCR4-tropic HIV-1 strains. This approach identified a 16

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