PHR1663

Propofol

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: 2,6-Diisopropylphenol, 2,6-Bis(1-methylethyl)phenol, 2,6-Bis(isopropyl)phenol, Propofol
• Lineáris képlet: [(CH₃)₂CH]₂C₆H₃OH
• CAS-szám: 2078-54-8
• Molekulatömeg: 178.27
• EC-szám: 218-206-6
• MDL-szám: MFCD00008885
• UNSPSC kód: 41116107
• PubChem Substance ID: 329823540
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to BP 1031; traceable to Ph. Eur. Y0000016; traceable to USP 1572503
• gőznyomás: 5.6 mmHg ( 100 °C)
• API-család: propofol
• Analitikai műbizonylat: current certificate can be downloaded
• kiszerelés: ampule of 1 mL
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• törésmutató: n20/D 1.514 (lit.)
• bp: 256 °C/764 mmHg (lit.)
• mp: 18 °C (lit.)
• sűrűség: 0.962 g/mL at 25 °C (lit.)
• alkalmazás(ok): pharmaceutical (small molecule)
• format: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: CC(C)c1cccc(C(C)C)c1O
• InChI: 1S/C12H18O/c1-8(2)10-6-5-7-11(9(3)4)12(10)13/h5-9,13H,1-4H3
• Nemzetközi kémiai azonosító kulcs: OLBCVFGFOZPWHH-UHFFFAOYSA-N
• Géninformáció: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Propofol is approved for induction and maintenance of paediatric anesthesia and sedation in children less than 3 years of age. The mechanism of action involves interaction with gamma-aminobutyric acid A receptor. Rapid effect and fewer side effects like postoperative nausea makes propofol a popular intravenous anesthetic agents.

Alkalmazás

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Propofol may be used as a pharmaceutical reference standard for the determination of the analyte in emulsion dosage form by sequential injection technique with spectrophotometric and fluorimetric detections.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAA5999 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Javasolt termékek

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Biztonsági adatok

• Piktogramok: GHS07
• Figyelmeztetés: Warning
• Figyelmeztető mondatok: H302,H315,H319,H335
• Óvintézkedésre vonatkozó mondatok: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Veszélyességi osztályok: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Célzott szervek: Respiratory system
• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 3
• Lobbanási pont (F): 235.4 °F - closed cup
• Lobbanási pont (C): 113 °C - closed cup