Ugrás a tartalomra
Merck

PHR1349

Supelco

Beta Alanine

Pharmaceutical Secondary Standard; Certified Reference Material

Szinonimák:

β-Alanine, β-Ala, 3-Aminopropionic acid

Bejelentkezésa Szervezeti és Szerződéses árazás megtekintéséhez


About This Item

Lineáris képlet:
NH2CH2CH2COOH
CAS-szám:
Molekulatömeg:
89.09
Beilstein:
906793
EC-szám:
MDL-szám:
UNSPSC kód:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

certified reference material
pharmaceutical secondary standard

Minőségi szint

Ügynökség

traceable to USP 1012495

API-család

beta-alanine

Analitikai műbizonylat

current certificate can be downloaded

technika/technikák

HPLC: suitable
gas chromatography (GC): suitable

mp

202 °C (dec.) (lit.)

alkalmazás(ok)

pharmaceutical (small molecule)

Formátum

neat

tárolási hőmérséklet

2-30°C

SMILES string

NCCC(O)=O

InChI

1S/C3H7NO2/c4-2-1-3(5)6/h1-2,4H2,(H,5,6)

Nemzetközi kémiai azonosító kulcs

UCMIRNVEIXFBKS-UHFFFAOYSA-N

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Általános leírás

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Beta Alanine is a non-protein amino acid, widely available in plants as one of the precursors for the essential vitamin, pantothenate. It exhibits behavior of an osmoprotectant in microbial assays. It is also the precursor for beta-alanine betaine in the plant family Plumbaginaceae.

Alkalmazás

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biokémiai/fiziológiai hatások

β-Alanine, a β−amino acid, is a component of pantothenic acid and the rate-limiting amino acid in the biosynthesis of the histidinyl antioxidant dipeptides carnosine and anserine. Endogenous β-amino acid that is a nonselective agonist at glycine receptors and a ligand for the G protein-coupled orphan receptor, TGR7 (MrgD). β-Alanine flux plays a cytoprotective role by supporting the osmotic stability of marine organisms, preimplantation mouse embryos and mammalian cells exposed to hypoxic stress.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAC3952 in the slot below. This is an example certificate only and may not be the lot that you receive.

kapcsolódó termék

Product No.
Leírás
Árazás

Tárolási osztály kódja

13 - Non Combustible Solids

WGK

WGK 1

Lobbanási pont (F)

Not applicable

Lobbanási pont (C)

Not applicable


Analitikai tanúsítványok (COA)

Analitikai tanúsítványok (COA) keresése a termék sarzs-/tételszámának megadásával. A sarzs- és tételszámok a termék címkéjén találhatók, a „Lot” vagy „Batch” szavak után.

Már rendelkezik ezzel a termékkel?

Az Ön által nemrégiben megvásárolt termékekre vonatkozó dokumentumokat a Dokumentumtárban találja.

Dokumentumtár megtekintése

Physiology and Molecular Biology of Stress Tolerance in Plants (2006)
Partha Sardar et al.
The American journal of cardiology, 113(7), 1173-1177 (2014-02-12)
Dabigatran is a novel oral anticoagulant and may be useful during atrial fibrillation (AF) ablation for prevention of thromboembolic events. However, the benefits and adverse effects of periprocedural dabigatran therapy have not been thoroughly evaluated. A meta-analysis was performed to
K E Tiedje et al.
Neurochemistry international, 57(3), 177-188 (2010-06-15)
This review discusses the role of beta-alanine as a neurotransmitter. Beta-alanine is structurally intermediate between alpha-amino acid (glycine, glutamate) and gamma-amino acid (GABA) neurotransmitters. In general, beta-alanine satisfies a number of the prerequisite classical criteria for being a neurotransmitter: beta-alanine
Julie Y Culbertson et al.
Nutrients, 2(1), 75-98 (2010-01-01)
Muscle carnosine has been reported to serve as a physiological buffer, possess antioxidant properties, influence enzyme regulation, and affect sarcoplasmic reticulum calcium regulation. Beta-alanine (β-ALA) is a non-essential amino acid. β-ALA supplementation (e.g., 2-6 grams/day) has been shown to increase
Ajay Yadlapati et al.
The American journal of cardiology, 113(8), 1362-1363 (2014-03-01)
Direct-current cardioversion (DCCV) for persistent atrial fibrillation or atrial flutter (AF) carries a risk of thromboembolic events (TEs). Therapeutic anticoagulation with warfarin is recommended for 3 to 4 weeks before and 4 weeks after DCCV to reduce TE; however, the

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