PHR1008

Ascorbic Acid

Pharmaceutical Secondary Standard; Certified Reference Material

• Szinonimák: L-Ascorbic acid, L-Threoascorbic acid, Antiscorbutic factor, Vitamin C
• Tapasztalati képlet (Hill-képlet): C₆H₈O₆
• CAS-szám: 50-81-7
• Molekulatömeg: 176.12
• Beilstein: 84272
• EC-szám: 200-066-2
• MDL-szám: MFCD00064328
• UNSPSC kód: 41116107
• PubChem Substance ID: 329823039
• E szám: E300
• NACRES: NA.24

Tulajdonságok

• grade: certified reference material; pharmaceutical secondary standard
• Minőségi szint: 300
• Ügynökség: traceable to BP 461; traceable to Ph. Eur. A1300000; traceable to USP 1043003
• API-család: ascorbic acid
• Forma: solid
• Analitikai műbizonylat: current certificate can be downloaded
• technika/technikák: HPLC: suitable; gas chromatography (GC): suitable
• mp: 190-194 °C (dec.)
• alkalmazás(ok): food and beverages
• Formátum: neat
• tárolási hőmérséklet: 2-8°C
• SMILES string: OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O
• InChI: 1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1
• Nemzetközi kémiai azonosító kulcs: CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Leírás

Általános leírás

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ascorbic acid is a powerful antioxidant and is widely used in pharmaceutical formulations.[1][2] It has proven to have a beneficial effect on age-related diseases such as cancer, atherosclerosis, ocular, neurodegenerative diseases, etc. It is mainly involved in the formation and maintenance of collagen.[3] The prolonged deficiency of ascorbic acid in diet may result in scurvy.[2]

Alkalmazás

Ascorbic Acid may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using hydrophilic interaction chromatography.[1]

Biokémiai/fiziológiai hatások

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. Ascorbic acid functions as an enzymatic cofactor for multiple enzymes, serving as an electron donor for monooxygenases and dioxygenases. Ascorbic acid also functions as a powerful antioxidant, particularly in regards to reactive oxygen species.

Analízis megjegyzés

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Egyéb megjegyzések

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Lábjegyzet

To see an example of a Certificate of Analysis for this material enter LRAC2886 in the slot below. This is an example certificate only and may not be the lot that you receive.

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable