14400

Biotin

≥99.0% (T)

• Szinonimák: D-Biotin, Bios II, Coenzyme R, Vitamin B7, Vitamin H
• Tapasztalati képlet (Hill-képlet): C₁₀H₁₆N₂O₃S
• CAS-szám: 58-85-5
• Molekulatömeg: 244.31
• Beilstein: 86838
• EC-szám: 200-399-3
• MDL-szám: MFCD00005541
• UNSPSC kód: 12352201
• eCl@ss: 34058011
• PubChem Substance ID: 329750287
• NACRES: NA.21

Tulajdonságok

• biológiai forrás: synthetic
• Minőségi szint: 200
• Teszt: ≥99.0% (T)
• Forma: powder
• optikai aktivitás: [α]20/D +91±2°, c = 1% in 0.1 M NaOH
• izzítási maradék: ≤0.1% (as SO₄)
• veszteség: ≤0.5% loss on drying
• szín: colorless to white
• mp: 229-234 °C; 231-233 °C (lit.)
• oldhatóság: alcohol: soluble 80mg/100 ml at 25 °C; water: soluble 22mg/100 ml at 25 °C; 0.1 M NaOH: 10 mg/mL at 25 °C, clear, colorless; H₂O: very soluble; organic solvents: insoluble
• kation nyomok: Ca: ≤50 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤10 mg/kg; K: ≤50 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Na: ≤500 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Zn: ≤5 mg/kg
• alkalmazás(ok): detection
• SMILES string: [H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
• InChI: 1S/C10H16N2O3S/c13-8(14)4-2-1-3-7-9-6(5-16-7)11-10(15)12-9/h6-7,9H,1-5H2,(H,13,14)(H2,11,12,15)/t6-,7-,9-/m0/s1
• Nemzetközi kémiai azonosító kulcs: YBJHBAHKTGYVGT-ZKWXMUAHSA-N

Leírás

Általános leírás

Biotin is readily available in several foods, like whole grains, nuts, legumes, unpolished rice and egg yolk. The normal gut flora also produces this vitamin.

Alkalmazás

Biotin has been used for testing the functionality of the Avidin-displaying phages. The product has also been used for labeling the swine anti-rabbit IgG antibody and peroxidase.

Biokémiai/fiziológiai hatások

Biotin acts as an important cofactor for carboxylase enzymes in various metabolic pathways. Biotin favors keratin synthesis and hence is used as a supplement for hair and nail growth. Deficiency of biotin shows several symptoms such as alopecia, conjunctivitis, seborrheic dermatitis, depression, lethargy, hypotonia and seizures.

Biotin also referred to as vitamin H or vitamin B7 is a water-soluble B-vitamin that induces two to three fold increase in guanylate cyclase activity in rat liver, kidney, colon, cerebellum, and heart. It also stimulates the sperm motility and prolongs the survival of cryopreserved human spermatozoa.

Egyéb megjegyzések

Reviews; Avidin-Biotin technology;

Biztonsági adatok

• Tárolási osztály kódja: 11 - Combustible Solids
• WGK: WGK 1
• Lobbanási pont (F): Not applicable
• Lobbanási pont (C): Not applicable
• Egyéni védőeszköz: Eyeshields, Gloves, type N95 (US)