1.37171

Polysorbate 80

high purity, EMPROVE^® EXPERT, Ph. Eur., ChP, JP, NF

• Szinonimák: TWEEN^® 80, POE (20) sorbitan monooleate, Polyethylene glycol sorbitan monooleate, Polyoxyethylenesorbitan monooleate, Polysorbate 80
• CAS-szám: 9005-65-6
• MDL-szám: MFCD00082107
• UNSPSC kód: 12352207
• EC index szám: 500-019-9

Tulajdonságok

• biológiai forrás: synthetic
• Minőségi szint: 500
• grade: GDP; GMP; Halal; Kosher
• Ügynökség: ChP; JP; NF; Ph. Eur.
• leírás: GMO free; low in endotoxins
• termékcsalád: EMPROVE^® EXPERT
• Forma: liquid
• hatékonyság: 42200 mg/kg LD₅₀, oral
• molekulatömeg: 1310 g/mol
• pH: 5-7 (20 °C, 50 g/L)
• bp: >100 °C
• sűrűség: 1.07 g/cm³ at 25 °C
• alkalmazás(ok): liquid formulation; parenterals; pharmaceutical
• idegen aktivitás: Aflatoxin free
• tárolási hőmérséklet: 15-25°C
• SMILES string: CCCCCCCC/C=C/CCCCCCCC(=O)OCCOCC(C1C(CC(O1)OCCO)OCCO)OCCO
• InChI: 1S/C32H60O10/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-30(36)40-25-24-37-27-29(39-22-19-34)32-28(38-21-18-33)26-31(42-32)41-23-20-35/h9-10,28-29,31-35H,2-8,11-27H2,1H3/b10-9+
• Nemzetközi kémiai azonosító kulcs: RGPBUVUVZKQNHD-MDZDMXLPSA-N

Leírás

Általános leírás

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove^® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC^® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Alkalmazás

Polysorbate 80 is used to stabilize biomolecule formulations and as solubilizer, emulsifier and wetting agent in small molecule formulations. Polysorbates are known to degrade via autoxidation and hydrolysis. Degradation products can have a negative impact on the stability of the protein as well as the small molecule API. To reduce this risk, the polysorbate high-purity grade contains a low amount of impurities, especially peroxide.

Intended for high-risk applications, this Emprove^® Expert grade contains bioburden and endotoxin limits.

Kiszerelés

1371710100 / 100ml / glass bottle
1371711000 / 1L / glass bottle

Jogi információk

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

TWEEN is a registered trademark of Croda International PLC

Biztonsági adatok

• Tárolási osztály kódja: 10 - Combustible liquids
• WGK: WGK 1
• Lobbanási pont (F): 235.4 °F - closed cup
• Lobbanási pont (C): > 113 °C - closed cup